Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.45 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.45 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3125776 | 0.81 | CYP3A4 (0.59) | CYP3A4TSHRTLR2TLR1TLR6 | |
| SCHEMBL4687669 | 0.81 | ALDH1A1 (0.52) | CYP3A4ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL15092 | 0.80 | CYP3A4 (1.00) | CYP3A4TSHRALDH1A1HPGDHSD17B10 | |
| SCHEMBL10594316 | 0.80 | CYP3A4 (0.47) | CYP3A4TSHRALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13632546 | 0.79 | TLR2 (0.51) | CYP3A4TSHRTLR2TLR1TLR6 | |
| Hydrochloric Acid SCHEMBL10392666 | 0.79 | ALDH1A1 (0.50) | CYP3A4ALDH1A1MEN1KMT2AHPGD | |
| Methane SCHEMBL5177350 | 0.79 | ALDH1A1 (0.50) | CYP3A4ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL27943596 | 0.79 | CYP3A4 (0.46) | CYP3A4TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL27946613 | 0.78 | CYP3A4 (0.95) | CYP3A4TSHRALDH1A1HPGDTDP1 | |
| SCHEMBL5502031 | 0.78 | CYP3A4 (0.46) | CYP3A4TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851473-B2 | Amide compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-14 | — | — | US | disclosed |
| US-20080312226-A1 | Amide Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-18 | — | — | US | disclosed |
| EP-1813606-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-08-01 | — | — | EP | disclosed |
| WO-2005019193-A2 | PHENYLUREA DERIVATIVES USEFUL IN THE TREATMENT OF CONDITIONS MEDIATED BY POLO-LIKE KINASES (PLK) | SMITHKLINE BEECHAM CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312226-A1 | Amide Compound | FAAH, FAAH2, CNR2 | CYP3A4 768/4885TSHR 819/4885TLR2 1788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.