SCHEMBL3766616

SCHEMBL3766616

O=C(O)SSc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.55
HSD17B10 Q99714 3/20 0.55
MAPT P10636 3/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
MGLL Q99685 1/20 0.55
FFAR1 O14842 1/20 0.44
CYP1A2 P05177 2/20 0.41
CYP2C9 P11712 1/20 0.41
ALDH1A1 P00352 6/20 0.40
POLB P06746 2/20 0.39
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
TSHR P16473 2/20 0.38
DAO P14920 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
ALOX15 P16050 1/20 0.38
PLIN1 O60240 1/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
PLIN5 Q00G26 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperidine SCHEMBL6518941 0.82 HSD17B10 (0.38) HPGDHSD17B10MAPTSMN1; SMN2MGLL
SCHEMBL11874395 0.82 HPGD (0.52) HPGDHSD17B10MAPTSMN1; SMN2MGLL
SCHEMBL28144870 0.80 MAPT (0.50) HPGDHSD17B10MAPTSMN1; SMN2MGLL
SCHEMBL200594 0.80 HPGD (0.50) HPGDHSD17B10MAPTSMN1; SMN2MGLL
SCHEMBL11621561 0.78 HPGD (0.48) HPGDHSD17B10MAPTSMN1; SMN2MGLL
SCHEMBL4183717 0.78 HPGD (0.48) HPGDHSD17B10MAPTSMN1; SMN2MGLL
Urea SCHEMBL27863158 0.76 HPGD (0.67) HPGDHSD17B10MAPTSMN1; SMN2MGLL
SCHEMBL775894 0.75 HPGD (0.50) HPGDHSD17B10MAPTSMN1; SMN2MGLL
SCHEMBL11615005 0.75 HSD17B10 (0.50) HPGDHSD17B10MAPTSMN1; SMN2MGLL
SCHEMBL31543780 0.75 HPGD (0.44) HPGDHSD17B10MAPTSMN1; SMN2MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12064239-B2 Device and methods for detection and monitoring of tuberculosis TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2024-08-20 US disclosed
EP-4264260-A1 METHODS FOR DIAGNOSING CANCER BASED ON VOLATILE ORGANIC COMPOUNDS IN BLOOD AND URINE SAMPLES TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2023-10-25 EP disclosed
WO-2022137232-A1 METHODS FOR DIAGNOSING CANCER BASED ON VOLATILE ORGANIC COMPOUNDS IN BLOOD AND URINE SAMPLES TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (IL) 2022-06-30 WO disclosed
EP-1892256-B1 AROMATIC POLYMER SUMITOMO CHEMICAL CO (JP) 2014-03-19 EP disclosed
US-7852434-B2 Aromatic polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-14 US disclosed
US-20090207346-A1 Aromatic polymer SUMITOMO CHEMICAL COMPANY,LIMITED (JP) 2009-08-20 US disclosed
EP-1892256-A1 AROMATIC POLYMER Sumitomo Chemical Company, Limited (JP) 2008-02-27 EP disclosed
EP-0627657-B1 Water-soluble disulfides in silver halide emulsions EASTMAN KODAK CO (US) 1997-07-16 EP disclosed
US-5418127-A Antifogging agent EASTMAN KODAK COMPANY (US) 1995-05-23 US disclosed
EP-0627657-A2 Water-soluble disulfides in silver halide emulsions EASTMAN KODAK COMPANY (US) 1994-12-07 EP disclosed