Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3766616 | 0.82 | HPGD (0.55) | HSD17B10SMN1; SMN2HPGDMAPTMGLL | |
| Phthalic Acid SCHEMBL5875074 | 0.71 | ALDH1A1 (0.61) | HSD17B10SMN1; SMN2HPGDMAPTSIGMAR1 | |
| Benzoic Acid SCHEMBL1716154 | 0.71 | TSHR (0.61) | HSD17B10SMN1; SMN2HPGDSIGMAR1NPC1 | |
| Benzoic Acid SCHEMBL1249244 | 0.71 | TSHR (0.61) | HSD17B10SMN1; SMN2HPGDSIGMAR1NPC1 | |
| Benzophenone SCHEMBL3444030 | 0.71 | ALDH1A1 (0.61) | HSD17B10SMN1; SMN2HPGDMAPTSIGMAR1 | |
| Phthalic Acid SCHEMBL5875064 | 0.71 | ALDH1A1 (0.61) | HSD17B10SMN1; SMN2HPGDMAPTSIGMAR1 | |
| Benzoic Acid SCHEMBL1088757 | 0.69 | TSHR (0.58) | HSD17B10SMN1; SMN2HPGDSIGMAR1NPC1 | |
| Benzoic Acid SCHEMBL2492854 | 0.69 | TSHR (0.64) | HSD17B10SIGMAR1KMT2AALDH1A1USP2 | |
| Phenylacetic Acid SCHEMBL9555521 | 0.68 | AKR1B1 (0.68) | HPGDKMT2AFFAR1ALDH1A1POLB | |
| Benzamide SCHEMBL694831 | 0.68 | TSHR (0.64) | HSD17B10SMN1; SMN2HPGDMAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050008568-A1 | Technetium or rhenium complexes, radiopharmaceutical products comprising them | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-13 | — | — | US | disclosed |
| EP-1453841-A1 | TECHNETIUM OR RHENIUM COMPLEXES, RADIOPHARMACEUTICAL PRODUCTS COMPRISING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003044031-A1 | TECHNETIUM OR RHENIUM COMPLEXES, RADIOPHARMACEUTICAL PRODUCTS COMPRISING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050008568-A1 | Technetium or rhenium complexes, radiopharmaceutical products comprising them | TSHR, MRPS35, TFRC | HSD17B10 2522/4885SMN1; SMN2 4861/4885HPGD 4653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.