Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11616112 | 0.80 | HPGD (0.41) | HSD17B10HPGDSMN1; SMN2MAPTTSHR | |
| SCHEMBL10144329 | 0.78 | TSHR (0.46) | HSD17B10HPGDSMN1; SMN2MAPTMGLL | |
| SCHEMBL19401304 | 0.78 | KDM4E (0.49) | HSD17B10HPGDSMN1; SMN2TSHRKMT2A | |
| Fluoride SCHEMBL27784131 | 0.77 | TSHR (0.45) | HSD17B10HPGDSMN1; SMN2MAPTMGLL | |
| SCHEMBL200594 | 0.76 | HPGD (0.50) | HSD17B10HPGDSMN1; SMN2MAPTMGLL | |
| SCHEMBL3766616 | 0.75 | HPGD (0.55) | HSD17B10HPGDSMN1; SMN2MAPTMGLL | |
| SCHEMBL11874395 | 0.73 | HPGD (0.52) | HSD17B10HPGDSMN1; SMN2MAPTMGLL | |
| Urea SCHEMBL27863158 | 0.72 | HPGD (0.67) | HSD17B10HPGDSMN1; SMN2MAPTMGLL | |
| SCHEMBL10862913 | 0.72 | SMN1; SMN2 (0.43) | HSD17B10HPGDSMN1; SMN2MAPTMGLL | |
| SCHEMBL28144870 | 0.71 | MAPT (0.50) | HSD17B10HPGDSMN1; SMN2MAPTMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4085094-A | SULFENYLTHIOCARBONATES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-04-18 | — | — | US | disclosed |