Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3766616 | 0.80 | HPGD (0.55) | HPGDHSD17B10MAPTSMN1; SMN2MGLL | |
| SCHEMBL8508100 | 0.79 | HPGD (0.42) | HPGDHSD17B10MAPTSMN1; SMN2MGLL | |
| SCHEMBL11874395 | 0.78 | HPGD (0.52) | HPGDHSD17B10MAPTSMN1; SMN2MGLL | |
| SCHEMBL28144870 | 0.76 | MAPT (0.50) | HPGDHSD17B10MAPTSMN1; SMN2MGLL | |
| SCHEMBL11615005 | 0.76 | HSD17B10 (0.50) | HPGDHSD17B10MAPTSMN1; SMN2MGLL | |
| SCHEMBL342299 | 0.75 | CA12 (0.54) | HPGDHSD17B10MAPTSMN1; SMN2MGLL | |
| SCHEMBL4183717 | 0.74 | HPGD (0.48) | HPGDHSD17B10MAPTSMN1; SMN2MGLL | |
| SCHEMBL11621561 | 0.74 | HPGD (0.48) | HPGDHSD17B10MAPTSMN1; SMN2MGLL | |
| Acetophenone SCHEMBL28222172 | 0.74 | HPGD (0.67) | HPGDHSD17B10MAPTSMN1; SMN2MGLL | |
| Urea SCHEMBL27863158 | 0.72 | HPGD (0.67) | HPGDHSD17B10MAPTSMN1; SMN2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1625 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4725949-A1 | IMPROVED SOLID-PHASE PHOSPHORAMIDITE-SYNTHESIS OF LONG OLIGONUCLEOTIDE MOLECULES | BioSpring Gesellschaft für Biotechnologie mbH (DE) | 2026-04-15 | — | — | EP | claimed |
| EP-4725950-A1 | IMPROVED SOLID-PHASE PHOSPHORAMIDITE-SYNTHESIS OF LONG OLIGONUCLEOTIDE MOLECULES | BioSpring Gesellschaft für Biotechnologie mbH (DE) | 2026-04-15 | — | — | EP | claimed |
| US-20260097383-A1 | SOLID-PHASE PHOSPHORAMIDITE-SYNTHESIS OF LONG OLIGONUCLEOTIDE MOLECULES | BioSpring Gesellschaft für Biotechnologie mbH (DE) | 2026-04-09 | — | — | US | claimed |
| US-12492220-B2 | Method for the preparation of oligonucleotides | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2025-12-09 | — | — | US | claimed |
| US-12435105-B2 | Technologies for oligonucleotide preparation | WAVE LIFE SCIENCES LTD. (SG) | 2025-10-07 | — | — | US | claimed |
| US-12264174-B2 | Process for preparing imetelstat | GERON CORPORATION (US) | 2025-04-01 | — | — | US | claimed |
| EP-4526944-A1 | THTOCARBONATE COMPOSITIONS FOR LITHIUM- SULFUR BATTERIES | Conamix Inc. (US) | 2025-03-26 | — | — | EP | claimed |
| CN-113631564-B | Method for producing oligonucleotide having phosphorothioate site | 味之素株式会社 | 2025-02-25 | — | — | CN | claimed |
| CN-114573652-B | Process for synthesizing medicinal nucleic acid | 安徽瑞拜药业有限公司 | 2025-02-07 | — | — | CN | claimed |
| EP-3475292-B1 | SYNTHESIS OF THIOLATED OLIGONUCLEOTIDES WITHOUT A CAPPING STEP | BIOGEN MA INC (US) | 2024-09-18 | — | — | EP | claimed |
| EP-1386925-A1 | Method for preparing oligonucleotides | Girindus AG (DE) | 2004-02-04 | — | — | EP | claimed |
| US-20030212267-A1 | Synthesis of sulfurized oligonucleotides | IONIS PHARMACEUTICALS, INC. | 2003-11-13 | — | — | US | claimed |
| EP-1246833-A4 | IMPROVED SYNTHESIS OF SULFURIZED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS INC (US) | 2003-04-09 | — | — | EP | claimed |
| EP-1246833-A1 | IMPROVED SYNTHESIS OF SULFURIZED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 2002-10-09 | — | — | EP | claimed |
| WO-2001051502-A1 | IMPROVED SYNTHESIS OF SULFURIZED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 2001-07-19 | — | — | WO | claimed |
| US-6242591-B1 | Synthesis of sulfurized 2'-substituted oligonucleotides | ISIS PHARMACEUTICALS, INC. | 2001-06-05 | — | — | US | claimed |
| EP-1023310-A4 | IMPROVED SYNTHESIS OF SULFURIZED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS INC (US) | 2001-05-16 | — | — | EP | claimed |
| US-6114519-A | PHOSPHITYLATION; OXIDATION ACYL DISULFIDE | ISIS PHARMACEUTICALS, INC. (US) | 2000-09-05 | — | — | US | claimed |
| EP-1023310-A1 | IMPROVED SYNTHESIS OF SULFURIZED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 2000-08-02 | — | — | EP | claimed |
| WO-1999019340-A1 | IMPROVED SYNTHESIS OF SULFURIZED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1999-04-22 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260097383-A1 | SOLID-PHASE PHOSPHORAMIDITE-SYNTHESIS OF LONG OLIGONUCLEOTIDE MOLECULES | RNGTT, NSUN2, RNMT | HPGD 4835/4885HSD17B10 4511/4885MAPT 3290/4885 |
| US-12435105-B2 | Technologies for oligonucleotide preparation | POLRMT, DCLRE1B, RNGTT | HPGD 4878/4885HSD17B10 3496/4885MAPT 1403/4885 |
| US-12492220-B2 | Method for the preparation of oligonucleotides | POLN, POLRMT, POLI | HPGD 4026/4885HSD17B10 4366/4885MAPT 3637/4885 |
| US-12264174-B2 | Process for preparing imetelstat | TERT, RNGTT, TRMT1L | HPGD 3465/4885HSD17B10 2985/4885MAPT 1169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.