Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3766976 | 0.80 | CA1 (0.47) | RAB9ANPC1HPGDNPSR1SMN1; SMN2 | |
| SCHEMBL1422925 | 0.75 | HDAC1 (0.36) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL290900 | 0.74 | RAB9A (0.50) | RAB9ANPC1HPGDNPSR1SMN1; SMN2 | |
| SCHEMBL3767941 | 0.73 | CA2 (0.38) | KMT2AMEN1ALDH1A1CA1CA2 | |
| SCHEMBL2057808 | 0.73 | CA2 (0.31) | TSHRALDH1A1CA1CA2CA9 | |
| SCHEMBL2057200 | 0.73 | CA2 (0.31) | TSHRALDH1A1CA1CA2CA9 | |
| SCHEMBL2057646 | 0.73 | CA2 (0.31) | CA1CA2 | |
| SCHEMBL2057905 | 0.73 | CA2 (0.31) | CA1CA2 | |
| SCHEMBL2057558 | 0.71 | — | — | |
| SCHEMBL2058048 | 0.71 | CA1 (0.31) | TSHRALDH1A1CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007363-A2 | PREPARATION OF FLUORINE-LABELLED COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2010-01-21 | — | — | WO | disclosed |
| WO-2010007363-A2 | PREPARATION OF FLUORINE-LABELLED COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2010-01-21 | — | — | WO | disclosed |