Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290900 | 0.83 | RAB9A (0.50) | RAB9ANPC1HPGDNPSR1SMN1; SMN2 | |
| SCHEMBL3766974 | 0.80 | RAB9A (0.40) | CA1CA2RAB9ANPC1HPGD | |
| SCHEMBL2904034 | 0.76 | KMT2A (0.48) | CA1CA2HPGDNPSR1SMN1; SMN2 | |
| SCHEMBL29366293 | 0.75 | KMT2A (0.49) | CA1CA2HPGDNPSR1SMN1; SMN2 | |
| SCHEMBL1470558 | 0.75 | KMT2A (0.49) | CA1CA2HPGDNPSR1SMN1; SMN2 | |
| SCHEMBL8690834 | 0.73 | SMN1; SMN2 (0.52) | RAB9AHPGDSMN1; SMN2MAPTTDP1 | |
| SCHEMBL8688303 | 0.73 | SMN1; SMN2 (0.52) | RAB9AHPGDSMN1; SMN2MAPTTDP1 | |
| SCHEMBL15432779 | 0.73 | RAB9A (0.43) | RAB9ANPC1HPGDNPSR1SMN1; SMN2 | |
| SCHEMBL7900307 | 0.73 | SMN1; SMN2 (0.52) | RAB9AHPGDSMN1; SMN2MAPTTDP1 | |
| SCHEMBL14015387 | 0.72 | SMN1; SMN2 (0.54) | RAB9ANPC1HPGDNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007363-A2 | PREPARATION OF FLUORINE-LABELLED COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2010-01-21 | — | — | WO | disclosed |