SCHEMBL3767258

SCHEMBL3767258

NC(=O)CC1=COCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4753939 0.81
SCHEMBL5912859 0.80 CAPN1 (0.34)
SCHEMBL4753907 0.79
SCHEMBL4751568 0.75 HSP90AB1 (0.39)
SCHEMBL21239894 0.75 POLB (0.40)
SCHEMBL7141390 0.72 CA2 (0.31)
SCHEMBL4026431 0.70
SCHEMBL28475451 0.62
SCHEMBL6205433 0.62 CA2 (0.33)
Oxalic Acid SCHEMBL6090649 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4373824-A1 IMMUNOCONJUGATES AND METHODS Zeno Management, Inc. (US) 2024-05-29 EP disclosed
WO-2023004266-A1 IMMUNOCONJUGATES AND METHODS RECURIUM IP HOLDINGS, LLC (US) 2023-01-26 WO disclosed
CN-108368060-B Pyrimidine derivative kinase inhibitors 中国科学院合肥物质科学研究院 2020-09-15 CN disclosed
EP-2203456-A2 NOVEL METHOD FOR PREPARING (POLY)AMINOALKYLAMINOACETAMIDE DERIVATIVES OF EPIPODOPHYLLOTOXIN, WHICH CAN BE USED IN THERAPEUTICS AS AN ANTICANCER AGENT Pierre Fabre Medicament (FR) 2010-07-07 EP disclosed
WO-2009050365-A2 NOVEL METHOD FOR PREPARING (POLY)AMINOALKYLAMINOACETAMIDE DERIVATIVES OF EPIPODOPHYLLOTOXIN, WHICH CAN BE USED IN THERAPEUTICS AS AN ANTICANCER AGENT PIERRE FABRE MEDICAMENT (FR) 2009-04-23 WO disclosed
WO-2002064558-A2 OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS SANKYO COMPANY, LIMITED (JP) 2002-08-22 WO disclosed