Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | ADK | P55263 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | VCP | P55072 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3767684 | 0.77 | CSNK1A1 (0.41) | NISCHMTORADKALDH1A1KMT2A | |
| SCHEMBL3765764 | 0.71 | — | — | |
| SCHEMBL1663671 | 0.70 | CSNK1A1 (0.53) | NISCHMTORADKALDH1A1KMT2A | |
| SCHEMBL38662055 | 0.70 | CSNK1A1 (0.53) | NISCHMTORADKALDH1A1KMT2A | |
| SCHEMBL8596176 | 0.69 | TAAR1 (0.39) | NISCHMTORADKALDH1A1KMT2A | |
| SCHEMBL711033 | 0.66 | LMNA (0.55) | ALDH1A1KMT2AMEN1TRIM24TRIM33 | |
| SCHEMBL9689968 | 0.66 | KMT2A (0.42) | ALDH1A1KMT2AMEN1TRIM24TRIM33 | |
| SCHEMBL6002606 | 0.66 | ADRA2A (0.52) | NISCHMTORADKALDH1A1KMT2A | |
| Benzene SCHEMBL28197607 | 0.65 | LMNA (0.52) | ALDH1A1KMT2AMEN1TRIM24TRIM33 | |
| SCHEMBL11098154 | 0.65 | NISCH (0.46) | NISCHMTORADKALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193132-A2 | 3-SPIROPYRIMIDINETRIONE-QUINOLINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | AstraZeneca AB (SE) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009004382-A2 | 3-SPIROPYRIMIDINETRIONE-QUINOLINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2009-01-08 | — | — | WO | disclosed |