Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.61 |
| ▸ | SKP1 | P63208 | 2/20 | 0.61 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.61 |
| ▸ | AR | P10275 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GBA1 | P04062 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18939632 | 0.87 | CKS1B (0.46) | CKS1BSKP1SKP2ARMEN1 | |
| SCHEMBL27711575 | 0.86 | CKS1B (0.61) | CKS1BSKP1SKP2ARMEN1 | |
| SCHEMBL3768315 | 0.85 | AR (0.67) | CKS1BSKP1SKP2ARALDH1A1 | |
| SCHEMBL2357113 | 0.78 | CKS1B (0.57) | CKS1BSKP1SKP2ALDH1A1MAPT | |
| SCHEMBL16075329 | 0.78 | CKS1B (0.52) | CKS1BSKP1SKP2GBA1ACHE | |
| SCHEMBL22212846 | 0.77 | CKS1B (0.49) | CKS1BSKP1SKP2ACHEALDH1A1 | |
| SCHEMBL16075307 | 0.77 | CKS1B (0.49) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL1146899 | 0.77 | CKS1B (0.50) | CKS1BSKP1SKP2ARMEN1 | |
| SCHEMBL3768360 | 0.77 | NPC1 (0.70) | CKS1BSKP1SKP2 | |
| SCHEMBL16075328 | 0.76 | BTK (0.50) | CKS1BSKP1SKP2ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851473-B2 | Amide compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-14 | — | — | US | disclosed |
| US-20080312226-A1 | Amide Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-18 | — | — | US | disclosed |
| CN-101103007-A | Amide compound | TAKEDA PHARMACEUTICAL (JP) | 2008-01-09 | — | — | CN | disclosed |
| EP-1813606-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312226-A1 | Amide Compound | FAAH, FAAH2, CNR2 | CKS1B 2817/4885SKP1 675/4885SKP2 1732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.