⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL954658 | 0.87 | DGAT1 (0.34) | — | |
| SCHEMBL14962148 | 0.74 | DGAT1 (0.34) | — | |
| SCHEMBL2895572 | 0.72 | DGAT1 (0.33) | — | |
| SCHEMBL2888209 | 0.72 | DGAT1 (0.33) | — | |
| SCHEMBL6246780 | 0.71 | MPO (0.30) | — | |
| SCHEMBL21858254 | 0.71 | DGAT1 (0.34) | — | |
| SCHEMBL5928297 | 0.70 | MEN1 (0.39) | — | |
| SCHEMBL3500693 | 0.70 | DGAT1 (0.38) | — | |
| SCHEMBL17447753 | 0.69 | DGAT1 (0.34) | — | |
| SCHEMBL21962054 | 0.69 | DGAT1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7842711-B2 | Indazolecarboxamide derivatives for the treatment and prevention of malaria | SANOFI-AVENTIS (FR) | 2010-11-30 | — | — | US | disclosed |
| US-20070185187-A1 | INDAZOLECARBOXAMIDE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF MALARIA | SANOFI-AVENTIS (FR) | 2007-08-09 | — | — | US | disclosed |