Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL954658 | 0.79 | DGAT1 (0.34) | — | |
| SCHEMBL19015017 | 0.78 | — | — | |
| SCHEMBL1581682 | 0.77 | — | — | |
| SCHEMBL7260575 | 0.77 | ALDH1A1 (0.41) | — | |
| SCHEMBL17508623 | 0.77 | MEN1 (0.42) | — | |
| SCHEMBL671590 | 0.74 | — | — | |
| SCHEMBL26962749 | 0.73 | NLRP3 (0.39) | — | |
| SCHEMBL26388990 | 0.73 | — | — | |
| SCHEMBL24609489 | 0.72 | FFAR1 (0.57) | — | |
| SCHEMBL3768372 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157002-B1 | 1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE COMPOUNDS USEFUL IN THERAPY | PFIZER LTD (GB) | 2005-08-10 | — | — | EP | disclosed |
| EP-1157002-A1 | 1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE COMPOUNDS USEFUL IN THERAPY | Pfizer Limited (GB) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000051972-A1 | 1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2000-09-08 | — | — | WO | disclosed |