SCHEMBL3768573

SCHEMBL3768573

C#Cc1cc(OCCCCCCCCCCCCCCCC)c(C#C)cc1OCCCCCCCCCCCCCCCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.42
CHUK O15111 1/20 0.42
DAPK3 O43293 1/20 0.42
JAK2 O60674 1/20 0.42
ROCK2 O75116 1/20 0.42
PRKCG P05129 1/20 0.42
CDK1 P06493 1/20 0.42
PIM1 P11309 1/20 0.42
RPS6KB1 P23443 1/20 0.42
CDK2 P24941 1/20 0.42
AKT1 P31749 1/20 0.42
AKT2 P31751 1/20 0.42
MAPKAPK2 P49137 1/20 0.42
BLK P51451 1/20 0.42
RPS6KA3 P51812 1/20 0.42
JAK3 P52333 1/20 0.42
LIMK1 P53667 1/20 0.42
PRKCZ Q05513 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2832284 1.00 ALDH1A1 (0.44) ALDH1A1HPGDTSHRCHUKDAPK3
SCHEMBL3267005 1.00 ALDH1A1 (0.44) ALDH1A1HPGDTSHRCHUKDAPK3
SCHEMBL766704 1.00 ALDH1A1 (0.44) ALDH1A1HPGDTSHRCHUKDAPK3
SCHEMBL1777341 0.93 SMPD1 (0.43) ALDH1A1HPGDTSHRCHUKDAPK3
SCHEMBL13171445 0.92 ALDH1A1 (0.40) ALDH1A1HPGDTSHRCHUKDAPK3
SCHEMBL29353206 0.86 ALDH1A1 (0.39) ALDH1A1HPGDTSHRCHUKDAPK3
SCHEMBL19759295 0.84 SMPD1 (0.42) ALDH1A1HPGDSMPD1TRPV1ESR1
SCHEMBL2851634 0.83 ALDH1A1 (0.48) ALDH1A1HPGDCHUKDAPK3JAK2
SCHEMBL28041717 0.83 ALDH1A1 (0.45) ALDH1A1HPGDTSHRCHUKDAPK3
SCHEMBL28425205 0.81 ALDH1A1 (0.63) ALDH1A1HPGDPLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7842830-B2 Transition-metal charge-transport materials, methods of fabrication thereof, and methods of use thereof GEORGIA TECH RESEARCH CORPORATION (US) 2010-11-30 US disclosed
US-20080121870-A1 Transition-Metal Charge Transport Materials, Methods Of Fabrication Thereof, And Methods Of Use Thereof GEORGIA TECH RESEACH CORPORATION 2008-05-29 US disclosed
WO-2005123754-A2 TRANSITION-METAL CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF GEORGIA TECH RESEARCH CORPORATION (US) 2005-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080121870-A1 Transition-Metal Charge Transport Materials, Methods Of Fabrication Thereof, And Methods Of Use Thereof SLC39A3, SLC6A6, SLC6A9 ALDH1A1 2421/4885HPGD 2446/4885TSHR 4527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.