Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | SLC5A7 | Q9GZV3 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415723 | 0.80 | LRRK2 (0.51) | HRH3LRRK2 | |
| SCHEMBL30646269 | 0.71 | SGK1 (0.41) | HRH3 | |
| SCHEMBL5532727 | 0.70 | HRH3 (0.42) | HRH3SLC5A7CYP2D6CYP3A4 | |
| SCHEMBL27367434 | 0.70 | SGK1 (0.49) | HRH3 | |
| Hydrochloric Acid SCHEMBL2877795 | 0.69 | SLC5A7 (0.45) | HRH3SLC5A7CYP2D6CYP3A4 | |
| SCHEMBL15062002 | 0.67 | HRH3 (0.50) | HRH3 | |
| SCHEMBL27323644 | 0.66 | SGK1 (0.60) | — | |
| SCHEMBL20069050 | 0.66 | OGA (0.52) | HRH3 | |
| SCHEMBL5405638 | 0.66 | HRH3 (0.42) | HRH3 | |
| SCHEMBL19111213 | 0.66 | HRH3 (0.57) | HRH3SLC5A7CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317646-A1 | COMPOUNDS | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317646-A1 | COMPOUNDS | CBR3, CNR1, HCAR3 | HRH3 23/4885LRRK2 2208/4885SLC5A7 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.