SCHEMBL3769260

SCHEMBL3769260

Clc1ccccc1OCc1ccc(COc2ccccc2Cl)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 7/20 0.71
RXRA P19793 1/20 0.71
RXRB P28702 1/20 0.71
HDAC6 Q9UBN7 1/20 0.65
MEN1 O00255 5/20 0.59
KMT2A Q03164 5/20 0.59
ALDH1A1 P00352 2/20 0.59
NPSR1 Q6W5P4 2/20 0.59
NPC1 O15118 3/20 0.56
RAB9A P51151 3/20 0.56
TP53 P04637 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
MITF O75030 1/20 0.56
XBP1 P17861 1/20 0.56
NFKB1 P19838 1/20 0.56
NFKB2 Q00653 1/20 0.56
RELA Q04206 1/20 0.56
SCD O00767 1/20 0.54
HTT P42858 2/20 0.51
MAPT P10636 4/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3047774 0.93 HPGD (0.69) HPGDRXRARXRBHDAC6MEN1
SCHEMBL31556117 0.90 HPGD (0.61) HPGDRXRARXRBHDAC6MEN1
SCHEMBL16019017 0.87 MAPT (0.66) HPGDRXRARXRBHDAC6MEN1
SCHEMBL15331520 0.86 HPGD (0.60) HPGDRXRARXRBHDAC6MEN1
SCHEMBL2037499 0.86 HPGD (0.60) HPGDRXRARXRBHDAC6MEN1
SCHEMBL1749470 0.84 RXRA (1.00) HPGDRXRARXRBHDAC6MEN1
SCHEMBL5279014 0.83 HPGD (0.61) HPGDRXRARXRBHDAC6MEN1
SCHEMBL6553017 0.79 HPGD (0.66) HPGDRXRARXRBHDAC6MEN1
SCHEMBL9808263 0.78 L3MBTL1 (0.68) HPGDMEN1KMT2AALDH1A1NPC1
SCHEMBL668412 0.78 L3MBTL1 (0.52) HPGDRXRARXRBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8978553-B2 Heat-sensitive lithographic printing plates MITSUBISHI PAPER MILLS LIMITED (JP) 2015-03-17 US disclosed
US-20120192740-A1 FOUNTAIN SOLUTION COMPOSITION FOR LITHOGRAPHIC PRINTING PLATE AND LITHOGRAPHIC PRINTING METHOD MITSUBISHI PAPER MILLS LIMITED (JP) 2012-08-02 US disclosed
US-20100307359-A1 HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATES MITSUBISHI PAPER MILLS LIMITED (JP) 2010-12-09 US disclosed