Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | RXRA | P19793 | 1/20 | 0.58 |
| ▸ | RXRB | P28702 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 4/20 | 0.51 |
| ▸ | CASR | P41180 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16018989 | 0.87 | ABCB1 (0.68) | ABCB1RXRANPC1RAB9AHTR1A | |
| SCHEMBL3769260 | 0.87 | HPGD (0.71) | MAPTL3MBTL1TDP1HPGDRXRA | |
| SCHEMBL14882465 | 0.85 | HTR1A (0.53) | MAPTL3MBTL1TDP1ABCB1NPC1 | |
| SCHEMBL17050818 | 0.83 | MRGPRX4 (0.60) | ABCB1HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL31556117 | 0.82 | HPGD (0.61) | MAPTL3MBTL1TDP1HPGDRXRA | |
| SCHEMBL3047774 | 0.81 | HPGD (0.69) | MAPTL3MBTL1TDP1HPGDRXRA | |
| SCHEMBL12301149 | 0.81 | ABCB1 (0.60) | MAPTL3MBTL1TDP1ABCB1RXRA | |
| SCHEMBL9117427 | 0.81 | L3MBTL1 (0.90) | MAPTL3MBTL1TDP1HPGDNPC1 | |
| SCHEMBL4518756 | 0.79 | APP (0.60) | ABCB1NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL30145233 | 0.79 | ABCB1 (0.59) | MAPTABCB1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290515-B2 | Cephem derivative having catechol group | SHIONOGI & CO., LTD (JP) | 2016-03-22 | — | — | US | disclosed |
| US-20140256697-A1 | CEPHEM DERIVATIVE HAVING CATECHOL GROUP | SHIONOGI & CO., LTD. (JP) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256697-A1 | CEPHEM DERIVATIVE HAVING CATECHOL GROUP | COMT, CEP170, SLC6A3 | MAPT 1067/4885L3MBTL1 4550/4885TDP1 4139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.