SCHEMBL37694

SCHEMBL37694

CCN(CC)c1ccc2c(C)c(-c3ccc(N=C=S)cc3)c(=O)oc2c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 12/20 0.69
KDM4E B2RXH2 10/20 0.69
MAPT P10636 7/20 0.69
L3MBTL1 Q9Y468 5/20 0.69
HPGD P15428 5/20 0.69
HIF1A Q16665 2/20 0.69
SMN1; SMN2 Q16637 2/20 0.69
EP300 Q09472 1/20 0.63
HTT P42858 6/20 0.55
TDP1 Q9NUW8 4/20 0.55
ATM Q13315 6/20 0.53
GLA P06280 6/20 0.53
GAA P10253 2/20 0.53
KLK7 P49862 1/20 0.53
CASP1 P29466 5/20 0.47
CASP7 P55210 5/20 0.47
HSD17B10 Q99714 5/20 0.47
LMNA P02545 3/20 0.47
THRB P10828 1/20 0.47
CYP3A4 P08684 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29351705 1.00 ALDH1A1 (0.69) ALDH1A1KDM4EMAPTL3MBTL1HPGD
Ethylene SCHEMBL28055534 0.98 ALDH1A1 (0.67) ALDH1A1KDM4EMAPTL3MBTL1HPGD
SCHEMBL28649238 0.90 ALDH1A1 (0.71) ALDH1A1KDM4EMAPTL3MBTL1HPGD
Acetic Acid SCHEMBL723858 0.88 ALDH1A1 (0.57) ALDH1A1KDM4EMAPTL3MBTL1HPGD
SCHEMBL13869309 0.86 ALDH1A1 (0.86) ALDH1A1KDM4EMAPTL3MBTL1HPGD
SCHEMBL14160786 0.82 ALDH1A1 (0.75) ALDH1A1KDM4EMAPTL3MBTL1HPGD
SCHEMBL28720726 0.82 ALDH1A1 (0.75) ALDH1A1KDM4EMAPTL3MBTL1HPGD
SCHEMBL8132354 0.82 ALDH1A1 (1.00) ALDH1A1KDM4EMAPTL3MBTL1HPGD
SCHEMBL9341138 0.82 ALDH1A1 (0.62) ALDH1A1KDM4EMAPTL3MBTL1HPGD
SCHEMBL5590828 0.82 ALDH1A1 (0.78) ALDH1A1KDM4EMAPTL3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4083 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11725227-B2 Devices and methods for examining drug effects on microorganisms ESSENLIX CORPORATION (US) 2023-08-15 US claimed
US-20220237930-A1 CELL AGE CLASSIFICATION AND DRUG SCREENING FOUNTAIN THERAPEUTICS INC (US) 2022-07-28 US claimed
US-10961571-B2 Polymerase assay with a FRET substrate Life Technologies Corporation (US) 2021-03-30 US claimed
US-20200399675-A1 DEVICES AND METHODS FOR EXAMINING DRUG EFFECTS ON MICROORGANISMS ESSENLIX CORPORATION (US) 2020-12-24 US claimed
US-10605805-B2 Device and system for analyzing a sample, particularly blood, as well as methods of using the same ESSENLIX CORPORATION (US) 2020-03-31 US claimed
EP-3541960-A2 METHODS AND DEVICES FOR DETECTING HEPATITIS C VIRUS Quest Diagnostics Investments LLC (US) 2019-09-25 EP claimed
US-20190276904-A1 METHODS AND DEVICES FOR DETECTING HEPATITIS C VIRUS QUEST DIAGNOSTICS INVESTMENTS LLC (US) 2019-09-12 US claimed
US-10324009-B2 Bio/chemical assay devices and methods for simplified steps, small samples, accelerated speed, and ease-of-use ESSENLIX CORPORATION (US) 2019-06-18 US claimed
US-10301674-B2 Polymerase assay with a FRET substrate Life Technologies Corporation (US) 2019-05-28 US claimed
US-20190078133-A1 DETECTION AND IDENTIFICATION OF BACTERIA AND DETERMINATION OF ANTIBIOTIC SUSCEPTIBILITY USING BACTERIOPHAGE AND REPORTER MOLECULES CHARLES STARK DRAPER LABORATORY INC (US) 2019-03-14 US claimed
US-20050026150-A1 Molecular detection systems utilizing reiterative oligonucleotide synthesis RIBOMED BIOTECHNOLOGIES, INC. 2005-02-03 US claimed
US-20040234996-A1 Molecular detection systems utilizing reiterative oligonucleotide synthesis RIBOMED BIOTECHNOLOGIES, INC. 2004-11-25 US claimed
US-20040175724-A1 Molecular detection systems utilizing reiterative oligonucleotide synthesis DESIGNER GENES, INC. 2004-09-09 US claimed
EP-1451366-A2 MOLECULAR DETECTION SYSTEMS UTILIZING REITERATIVE OLIGONUCLEOTIDE SYNTHESIS Ribomed Biotechnologies, Inc. (US) 2004-09-01 EP claimed
US-20040157257-A1 Abortive promoter cassettes RIBOMED BIOTECHNOLOGIES, INC. (US) 2004-08-12 US claimed
US-20040137461-A1 Molecular detection systems utilizing reiterative oligonucleotide synthesis DESIGNER GENES, INC. 2004-07-15 US claimed
EP-1427854-A1 METHODS FOR QUANTIFYING NUCLEAR RUN-ON TRANSCRIPTIONAL ASSAYS Benitec Australia Ltd. (AU) 2004-06-16 EP claimed
US-20030099950-A1 Molecular detection systems utilizing reiterative oligonucleotide synthesis RIBOMED BIOTECHNOLOGIES, INC. 2003-05-29 US claimed
WO-2003038042-A2 MOLECULAR DETECTION SYSTEMS UTILIZING REITERATIVE OLIGONUCLEOTIDE SYNTHESIS RIBOMED BIOTECHNOLOGIES, INC. (US) 2003-05-08 WO claimed
WO-2003018832-A1 METHODS FOR QUANTIFYING NUCLEAR RUN-ON TRANSCRIPTIONAL ASSAYS BENITEC AUSTRALIA LTD (AU) 2003-03-06 WO claimed