SCHEMBL376947

SCHEMBL376947

CCCC(=O)OC(O)CC

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
LMNA P02545 4/20 0.43
TSHR P16473 2/20 0.42
MAPT P10636 2/20 0.39
MAPK1 P28482 1/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
FFAR3 O14843 2/20 0.36
HDAC3 O15379 2/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC2 Q92769 2/20 0.36
HDAC8 Q9BY41 2/20 0.36
PRKCA P17252 1/20 0.34
PRKCE Q02156 1/20 0.34
PRKCQ Q04759 1/20 0.34
PRKCD Q05655 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2129458 0.90 TSHR (0.46) ALDH1A1LMNATSHRMAPTMAPK1
SCHEMBL28684939 0.86 LMNA (0.53) ALDH1A1LMNATSHRMAPTMAPK1
SCHEMBL11093080 0.86 LMNA (0.47) ALDH1A1LMNATSHRMAPTMAPK1
SCHEMBL11159880 0.86 LMNA (0.52) ALDH1A1LMNATSHRMAPTMAPK1
SCHEMBL10419385 0.85 LMNA (0.62) ALDH1A1LMNAMAPTMAPK1PRKCA
SCHEMBL10884007 0.84 LMNA (0.55) ALDH1A1LMNAMAPTMAPK1PRKCA
SCHEMBL10430878 0.84 ALDH1A1 (0.48) ALDH1A1LMNATSHRMAPTMAPK1
SCHEMBL769294 0.83 LMNA (0.66) ALDH1A1LMNAMAPTMAPK1PRKCA
SCHEMBL545424 0.83 LMNA (0.66) ALDH1A1LMNAMAPTMAPK1PRKCA
SCHEMBL3028731 0.83 LMNA (0.66) ALDH1A1LMNAMAPTMAPK1PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2178519-B1 Nanoparticles comprising a non-ionizable polymer and an anionic cellulosic polymer BEND RES INC (US) 2012-04-25 EP claimed
US-8066880-B2 Apparatus for denitrifying wastewater HOOT AEROBIC SYSTEMS, INC. (US) 2011-11-29 US claimed
EP-1404302-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING ADSORBATES OF AMORPHOUS DRUG PFIZER PROD INC (US) 2010-11-03 EP claimed
WO-2010057976-A1 LIQUID SURFACE TREATMENT COMPOSITION WITH PHOSPHONIC ACID DERIVATIVES NEUTRALIZED WITH A BINARY AMINE SYSTEM THERMPHOS TRADING GMBH (CH) 2010-05-27 WO claimed
WO-2010057973-A1 SOLID SURFACE TREATMENT COMPOSITION CONTAINING AMINE NEUTRALIZED PHOSPHONATE THERMPHOS TRADING GMBH (CH) 2010-05-27 WO claimed
US-20090211957-A1 Apparatus For Denitrifying Wastewater CORMIER, TROY L. 2009-08-27 US claimed
US-8758556-B2 Composition for inhibiting calcium salt scale formation DEQUEST AG (CH) 2014-06-24 US disclosed
EP-2408721-B1 COMPOSITION FOR INHIBITING CALCIUM SALT SCALE FORMATION DEQUEST AG (CH) 2013-07-31 EP disclosed
US-8349772-B2 Method of secondary oil recovery using an aminoalkylene phosphonic acid and an amine neutralizing agent DEQUEST AG (CH) 2013-01-08 US disclosed
EP-2303983-B1 METHOD OF SECONDARY OIL RECOVERY DEQUEST AG (CH) 2012-09-19 EP disclosed
US-20120160438-A1 COMPOSITION FOR INHIBITING CALCIUM SALT SCALE FORMATION DEQUEST AG (CH) 2012-06-28 US disclosed
EP-2408721-A1 COMPOSITION FOR INHIBITING CALCIUM SALT SCALE FORMATION Dequest AG (CH) 2012-01-25 EP disclosed
US-20110130312-A1 METHOD OF SECONDARY OIL RECOVERY DEQUEST AG (CH) 2011-06-02 US disclosed
WO-2010000787-A1 METHOD OF SECONDARY OIL RECOVERY THERMPHOS TRADING GMBH (CH) 2010-01-07 WO disclosed
CN-100484772-C Image recording sheet and image recording method DAICEL CHEM (JP) 2009-05-06 CN disclosed
EP-1591264-B9 IMAGE RECORDING SHEET AND METHOD OF IMAGE RECORDING DAICEL CHEM (JP) 2007-10-24 EP disclosed
EP-1591264-B1 IMAGE RECORDING SHEET AND METHOD OF IMAGE RECORDING DAICEL CHEM (JP) 2007-06-06 EP disclosed
US-20060165920-A1 Image recording sheet and method of image recording DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-07-27 US disclosed
CN-1767952-A Image recording sheet and method of image recording DAICEL CHEM (JP) 2006-05-03 CN disclosed
EP-1591264-A1 IMAGE RECORDING SHEET AND METHOD OF IMAGE RECORDING Daicel Chemical Industries, Ltd. (JP) 2005-11-02 EP disclosed