Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 7/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 11/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 9/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.38 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.38 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935874 | 0.77 | SLC1A2 (0.44) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| SCHEMBL18775007 | 0.77 | SLC1A2 (0.45) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| SCHEMBL9587489 | 0.77 | SLC1A2 (0.44) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| SCHEMBL5295103 | 0.77 | PTGS1 (0.46) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| SCHEMBL12189727 | 0.76 | SLC1A2 (0.43) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| SCHEMBL7376089 | 0.76 | SLC1A2 (0.43) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| SCHEMBL18762462 | 0.76 | SLC1A2 (0.43) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| Chloromethane SCHEMBL29259265 | 0.75 | SLC7A5 (0.46) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| SCHEMBL18788848 | 0.74 | SLC1A2 (0.42) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| SCHEMBL5696083 | 0.74 | PTGS1 (0.44) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305056-A1 | CYSTEINE PROTEASE INHIBITORS FOR THE TREATMENT OF PARASITIC DISEASE | MERCK FROSST CANADA LTD. (CA) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305056-A1 | CYSTEINE PROTEASE INHIBITORS FOR THE TREATMENT OF PARASITIC DISEASE | CTSL, SERPINB1, CTSZ | SLC1A2 3170/4885SLC1A3 2343/4885SLC1A1 1977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.