Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.41 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3770265 | 0.94 | ALDH1A1 (0.51) | ALDH1A1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL3779414 | 0.83 | MMP2 (0.54) | CYP1A2CYP2C9CYP2C19MMP1MMP2 | |
| SCHEMBL3783014 | 0.82 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL3772347 | 0.81 | SLC6A4 (0.47) | CYP1A2CYP2C9CYP2C19SLC6A3 | |
| SCHEMBL3781291 | 0.80 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1MAPTPLIN1 | |
| SCHEMBL3785359 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2C19KMT2AMEN1 | |
| SCHEMBL3777053 | 0.77 | ALDH1A1 (0.39) | ALDH1A1MAPTPLIN1HPGDALOX15 | |
| SCHEMBL3787457 | 0.77 | MMP2 (0.44) | ALDH1A1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL3784242 | 0.77 | MMP2 (0.50) | CYP1A2CYP2C9CYP2C19MMP1MMP2 | |
| SCHEMBL3781516 | 0.75 | KMT2A (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324305-A1 | PRODUCTION METHOD OF POLYCYCLIC LACTAMS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-12-23 | — | — | US | disclosed |
| US-20090118519-A1 | Production Method of Polycyclic Lactams | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-05-07 | — | — | US | disclosed |
| EP-2014647-A1 | PROCESS FOR PRODUCING POLYCYCLIC LACTAM | Sumitomo Chemical Company, Limited (JP) | 2009-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118519-A1 | Production Method of Polycyclic Lactams | MRPL21, COASY, ASNS | ALDH1A1 1979/4885CYP1A2 53/4885CYP2C9 20/4885 |
| US-20100324305-A1 | PRODUCTION METHOD OF POLYCYCLIC LACTAMS | COASY, MRPL21, ASNS | ALDH1A1 1821/4885CYP1A2 38/4885CYP2C9 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.