Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 7/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.42 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3772459 | 0.97 | CYP1A2 (0.45) | KMT2ACYP2C19CYP1A2CYP2C9TDP1 | |
| SCHEMBL3787457 | 0.92 | MMP2 (0.44) | KMT2ACYP2C19CYP1A2CYP2C9KEAP1 | |
| SCHEMBL3781297 | 0.83 | KEAP1 (0.56) | CYP2C19CYP1A2CYP2C9KEAP1NFE2L2 | |
| SCHEMBL3779237 | 0.81 | ALDH1A1 (0.42) | KMT2ACYP2C19CYP1A2CYP2C9TDP1 | |
| SCHEMBL3787721 | 0.80 | KEAP1 (0.56) | CYP2C19CYP1A2CYP2C9KEAP1NFE2L2 | |
| SCHEMBL28797481 | 0.77 | SLC6A2 (0.43) | KMT2ACYP1A2SLC6A2SLC6A4HPGD | |
| SCHEMBL5407790 | 0.77 | CYP2C19 (0.51) | KMT2ACYP2C19CYP1A2CYP2C9TDP1 | |
| SCHEMBL5413316 | 0.77 | CYP2C19 (0.51) | KMT2ACYP2C19CYP1A2CYP2C9TDP1 | |
| SCHEMBL5407785 | 0.77 | CYP2C19 (0.51) | KMT2ACYP2C19CYP1A2CYP2C9TDP1 | |
| SCHEMBL20208692 | 0.75 | KEAP1 (0.79) | KEAP1NFE2L2L3MBTL1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324305-A1 | PRODUCTION METHOD OF POLYCYCLIC LACTAMS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-12-23 | — | — | US | disclosed |
| US-20090118519-A1 | Production Method of Polycyclic Lactams | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-05-07 | — | — | US | disclosed |
| EP-2014647-A1 | PROCESS FOR PRODUCING POLYCYCLIC LACTAM | Sumitomo Chemical Company, Limited (JP) | 2009-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118519-A1 | Production Method of Polycyclic Lactams | MRPL21, COASY, ASNS | KMT2A 1271/4885CYP2C19 50/4885CYP1A2 53/4885 |
| US-20100324305-A1 | PRODUCTION METHOD OF POLYCYCLIC LACTAMS | COASY, MRPL21, ASNS | KMT2A 1135/4885CYP2C19 43/4885CYP1A2 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.