SCHEMBL3771013

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3777522	0.88	PTGDR2 (0.45)	PTGDR2
	SCHEMBL3781729	0.88	ALDH1A1 (0.41)	KDM4ELMNAPLA2G2AKMT2ANPSR1
	SCHEMBL3771036	0.83	LMNA (0.38)	EGLN1PTGDR2ENPP2LMNAPLA2G2A
	SCHEMBL3779168	0.81	TDP1 (0.45)	EGLN1PTGDR2
	SCHEMBL3775557	0.80	KMT2A (0.40)	EGLN1ENPP2KDM4EKMT2ANPSR1
	SCHEMBL3777107	0.79	KDM4E (0.46)	EGLN1PTGDR2ENPP2KDM4ELMNA
	SCHEMBL3788385	0.79	PTGDR2 (0.43)	PTGDR2CYP2C9
	SCHEMBL27826435	0.78	KDM4E (0.38)	EGLN1ENPP2KDM4ELMNAPLA2G2A
	SCHEMBL3784536	0.78	EGLN1 (0.39)	EGLN1PTGDR2KDM4ELMNAALDH1A1
	SCHEMBL3780495	0.78	PTGDR2 (0.48)	EGLN1PTGDR2ENPP2KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.