SCHEMBL377180

SCHEMBL377180

C=C(CC(=O)O)CC(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.57
SRR Q9GZT4 1/20 0.57
ALOX15 P16050 2/20 0.43
HSD17B10 Q99714 1/20 0.43
LMNA P02545 3/20 0.38
EGLN1 Q9GZT9 2/20 0.38
ALKBH5 Q6P6C2 1/20 0.38
SUCNR1 Q9BXA5 1/20 0.38
TSHR P16473 4/20 0.35
FFAR3 O14843 1/20 0.35
GLRA1 P23415 1/20 0.35
SLC6A9 P48067 1/20 0.35
OR51E2 Q9H255 1/20 0.35
KDM4E B2RXH2 3/20 0.35
SLC22A6 Q4U2R8 2/20 0.33
KDM5C P41229 2/20 0.32
PHF8 Q9UPP1 2/20 0.32
KDM2A Q9Y2K7 2/20 0.32
KDM6B O15054 1/20 0.32
FOLH1 Q04609 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12927368 0.85 KDM4E (0.44) LDHASRRALOX15HSD17B10LMNA
SCHEMBL18432281 0.83
SCHEMBL2935618 0.83 LDHA (0.40) LDHASRRALOX15HSD17B10TSHR
SCHEMBL297939 0.81
SCHEMBL18106106 0.81
SCHEMBL3504717 0.81 EGLN1 (0.53) LDHASRRALOX15HSD17B10LMNA
SCHEMBL122476 0.81
SCHEMBL1980408 0.77
SCHEMBL23069971 0.76 LMNA (0.58) ALOX15HSD17B10LMNATSHROR51E2
Malonic Acid SCHEMBL132207 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 710 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250270596-A1 MEVALONATE DERIVATIVES AND METHODS FOR MAKING THE SAME UNIV DUKE (US) 2025-08-28 US claimed
EP-4561746-A1 FILTER AID COMPOSITE Imerys USA, Inc. (US) 2025-06-04 EP claimed
CN-119654191-A Filtering-aid composite material 英默里斯美国公司 2025-03-18 CN claimed
CN-119654190-A Microparticles of at least one of expanded ground perlite, diatomaceous earth, and sepiolite as absorbents 伊梅斯切公司 2025-03-18 CN claimed
US-20240093070-A1 AN ADHESIVE COMPOSITION ROHM AND HAAS COMPANY 2024-03-21 US claimed
WO-2024025920-A1 FILTER AID COMPOSITE IMERYS USA, INC. (US) 2024-02-01 WO claimed
EP-4311599-A1 GRANULATE OF AT LEAST ONE OF EXPANDED MILLED PERLITE, DIATOMACEOUS EARTH AND SEPIOLITE AS AN ABSORBENT ImerTech SAS (FR) 2024-01-31 EP claimed
EP-4073308-B1 NONWOVEN MAT WITH REDUCED PERMEABILITY AND INCREASED CALIPER OWENS CORNING INTELLECTUAL CAPITAL LLC (US) 2024-01-03 EP claimed
CN-114787439-B Nonwoven felt with reduced transmission and increased caliper size 欧文斯科宁知识产权资产有限公司 2024-01-02 CN claimed
WO-2023184755-A1 SPECIAL HIGH-WATER-RESISTANCE BIO-BASED FORMALDEHYDE-FREE SETTING AGENT FOR MINERAL WOOL 江苏艾科赛特新材料有限公司 2023-10-05 WO claimed
EP-1305375-A2 HARDENABLE COMPOSITIONS COMPRISING POLYACID(S) AND POLYOL(S) Valspar Corporation (US) 2003-05-02 EP claimed
US-20020156219-A1 High functionality number, low molecular weight polymers and methods of making same SWIMC LLC 2002-10-24 US claimed
WO-2002006412-A2 HARDENABLE COMPOSITIONS COMPRISING POLYACID(S) AND POLYOL(S) VALSPAR CORPORATION (US) 2002-01-24 WO claimed
EP-0512732-B1 Heat-resistant nonwoven ROHM & HAAS (US) 1998-09-09 EP claimed
CN-1068610-A HEAT-RESISTANT NONWOVEN FABRICS ROHM & HAAS (US) 1993-02-03 CN claimed
EP-0512732-A1 Heat-resistant nonwoven ROHM AND HAAS COMPANY (US) 1992-11-11 EP claimed
US-5143582-A Binder is carboxy containing polymer cured with hydroxyalkyl amide ROHM AND HAAS COMPANY (US) 1992-09-01 US claimed
US-4101606-A Method for curing polymers containing one or more carboxy or anhydride functions by means of polymers having hydroxyamide groups, and compositions ROHM AND HAAS COMPANY (US) 1978-07-18 US claimed
US-4076917-A HEAT CURING, FILMS ROHM AND HAAS COMPANY (US) 1978-02-28 US claimed
US-4003944-A Preparation of 2,4-dicyano-3,5-dimethylaniline BAYER AKTIENGESELLSCHAFT (DT) 1977-01-18 US claimed