SCHEMBL508395

SCHEMBL508395

O=[C]c1ccccc1N1C(=O)C=CC1=O

nearest known ligand 0.64

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 2/20 0.64
MGLL Q99685 15/20 0.53
FAAH O00519 5/20 0.48
HSP90AA1 P07900 4/20 0.44
ALDH1A1 P00352 2/20 0.44
PKM P14618 2/20 0.44
ATM Q13315 2/20 0.44
CCR6 P51684 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29510552 0.83 TLR9 (0.64) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL3771981 0.83 TLR9 (0.64) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL717690 0.82 TLR9 (0.61) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL121404 0.79 TLR9 (1.00) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL29377102 0.79 TLR9 (1.00) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL718678 0.79 TLR9 (0.57) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL1920666 0.78 MAPK1 (0.40) TLR9ALDH1A1
SCHEMBL7208771 0.77 TLR9 (0.46) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL5174463 0.76 TLR9 (0.44) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL30804538 0.75 TLR9 (0.57) TLR9MGLLFAAHHSP90AA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1675 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3798231-A1 CONJUGATED ANTI-CD38 ANTIBODIES Takeda Pharmaceutical Company Limited (JP) 2021-03-31 EP claimed
CN-104371124-A Crosslinked polymer film based on sydnone click chemistry and preparation method thereof UNIV EAST CHINA NORMAL 2015-02-25 CN claimed
JP-4800614-B2 2011-10-26 JP claimed
JP-2006507232-A 2006-03-02 JP claimed
EP-1534269-A1 OXIME CONJUGATES AND METHODS FOR THEIR FORMATION AND USE THE GENERAL HOSPITAL CORPORATION (US) 2005-06-01 EP claimed
WO-2004009082-A1 OXIME CONJUGATES AND METHODS FOR THEIR FORMATION AND USE THE GENERAL HOSPITAL CORPORATION (US) 2004-01-29 WO claimed
EP-0157797-A1 DETECTING AN IMMUNOLOGICAL REACTION WITH ACTIVATED RED BLOOD CELLS (ERYTHROCYTES) IMMUCOR, INC. (US) 1985-10-16 EP claimed
WO-1985001354-A1 DETECTING AN IMMUNOLOGICAL REACTION WITH ACTIVATED RED BLOOD CELLS (ERYTHROCYTES) IMMUCOR, INC. (US) 1985-03-28 WO claimed
JP-57158783-A None JP disclosed
WO-2024151890-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2024-07-18 WO disclosed
US-12036286-B2 Selective drug release from internalized conjugates of biologically active compounds SEAGEN INC. (US) 2024-07-16 US disclosed
US-12037403-B2 Compositions and methods for treating cancer with anti-CD123 immunotherapy LENTIGEN TECHNOLOGY, INC. (US) 2024-07-16 US disclosed
CN-118345102-A Compositions and methods for treating cancer with anti-CD 22 immunotherapy 莱蒂恩技术公司 2024-07-16 CN disclosed
CN-113286607-B Compositions and methods for treating cancer with anti-CD 19/CD22 immunotherapy 莱蒂恩技术公司 2024-07-12 CN disclosed
US-4323647-A IMMOBILIZED ENZYMES SEPARATION UNIVERSITY OF MIAMI (US) 1982-04-06 US disclosed
US-4276206-A GENERALLY APPLICABLE METHOD OF MAKING IMMUNOSUPPRESSIVE AGENTS SCRIPPS CLINIC & RESEARCH FOUNDATION (US) 1981-06-30 US disclosed
US-4253995-A PURIFICATION BY REACTING WITH BIOTIN AND SEPARATING ON AVIDIN COLUMN SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1981-03-03 US disclosed
US-4253996-A MALEIMIDE DERIVATIVE AS COUPLER FOR POLYPEPTIDES SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1981-03-03 US disclosed
EP-0015059-A2 Immunochemical conjugates: method and composition SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1980-09-03 EP disclosed
US-4220565-A Immunochemical conjugates: method and composition SCRIPPS CLINIC & RESEARCH FOUNDATION (US) 1980-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12036286-B2 Selective drug release from internalized conjugates of biologically active compounds CTSB, CTSE, CTSZ TLR9 1463/4885MGLL 1865/4885FAAH 669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.