SCHEMBL717690

SCHEMBL717690

C#Cc1ccccc1N1C(=O)C=CC1=O

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 2/20 0.61
MGLL Q99685 14/20 0.57
FAAH O00519 5/20 0.47
HSP90AA1 P07900 4/20 0.43
ALDH1A1 P00352 2/20 0.43
PKM P14618 2/20 0.43
ATM Q13315 2/20 0.43
CCR6 P51684 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL508395 0.82 TLR9 (0.64) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL29510552 0.82 TLR9 (0.64) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL3771981 0.82 TLR9 (0.64) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL121404 0.78 TLR9 (1.00) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL29377102 0.78 TLR9 (1.00) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL718678 0.77 TLR9 (0.57) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL29376713 0.72 MGLL (1.00) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL58050 0.72 MGLL (1.00) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL6832688 0.72 TLR9 (0.76) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL9084081 0.70 TLR9 (0.73) TLR9MGLLFAAHHSP90AA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4517364-A CROSSLINKING POYLMERS, DIELS-ALDER ADDITION REACTION PLASTICS ENGINEERING COMPANY (US) 1985-05-14 US claimed
US-9150414-B2 Nanocomposite and dispersion comprising the same KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2015-10-06 US disclosed
US-20120053288-A1 NANOCOMPOSITE AND DISPERSION COMPRISING THE SAME KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2012-03-01 US disclosed
US-4528349-A Polymerization products of vinylacetylene-terminated polyimide derivatives PLASTICS ENGINEERING COMPANY (US) 1985-07-09 US disclosed
US-4528373-A Vinylacetylene-terminated polyimide derivatives PLASTICS ENGINEERING COMPANY (US) 1985-07-09 US disclosed
US-4520198-A A DIEL-ALDER ADDITION PRODUCT WITH DIENOPHILE PLASTICS ENGINEERING COMPANY (US) 1985-05-28 US disclosed
US-4517363-A Vinylacetylene-terminated polyimide derivatives PLASTICS ENGINEERING COMPANY (US) 1985-05-14 US disclosed
US-4517364-A CROSSLINKING POYLMERS, DIELS-ALDER ADDITION REACTION PLASTICS ENGINEERING COMPANY (US) 1985-05-14 US disclosed
US-4451402-A MOLDING MATERIALS; VARNISHES; COATINGS PLASTICS ENGINEERING COMPANY (US) 1984-05-29 US disclosed
US-4435323-A CROSSLINKING PLASTICS ENGINEERING COMPANY (US) 1984-03-06 US disclosed
US-4405786-A Addition products of di-acetylene-terminated polyimide derivatives and an dienophile having ethylene groups PLASTICS ENGINEERING COMPANY (US) 1983-09-20 US disclosed
US-4405521-A Addition products of di-acetylene-terminated polyimide derivatives with a polyimide having terminal ethylenic groups PLASTICS ENGINEERING COMPANY (US) 1983-09-20 US disclosed
US-4405519-A Di-Acetylene-terminated polyimide derivatives PLASTICS ENGINEERING COMPANY (US) 1983-09-20 US disclosed
US-4405520-A Addition products of di-acetylene-terminated polymide derivatives and dienophiles having terminal maleimide grops PLASTICS ENGINEERING COMPANY (US) 1983-09-20 US disclosed
US-4404139-A MOLDING MATERIALS PLASTICS ENGINEERING COMPANY (US) 1983-09-13 US disclosed
US-4402878-A Addition products of di-acetylene-terminated polyimide derivatives with a polyimide having terminal non-conjugated acetylene groups PLASTICS ENGINEERING COMPANY (US) 1983-09-06 US disclosed
US-4377673-A LAMINATION; MOLDING MATERIALS; CROSSLINKING PLASTICS ENGINEERING COMPANY (US) 1983-03-22 US disclosed
US-4377525-A Addition products of diacetylene-terminated polyimide derivatives and a dienophile having a terminal vinyl group PLASTICS ENGINEERING COMPANY (US) 1983-03-22 US disclosed
US-4331794-A Polymerization products of diimides having terminal diacetylene groups PLASTICS ENGINEERING COMPANY (US) 1982-05-25 US disclosed
US-4331601-A POLYIMIDE MOLDING MATERIALS PLASTICS ENGINEERING COMPANY (US) 1982-05-25 US disclosed