Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LATS1 | O95835 | 1/20 | 0.32 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783009 | 0.86 | CA2 (0.41) | CA2CA12CA14DGAT1MAOA | |
| SCHEMBL6535041 | 0.82 | MAOA (0.44) | CA2CA12CA14DGAT1MAOA | |
| SCHEMBL9612246 | 0.80 | MAOA (0.43) | CA2CA12CA14DGAT1MAOA | |
| SCHEMBL7433191 | 0.80 | CA12 (0.50) | CA2CA12CA14DGAT1MAOA | |
| SCHEMBL763067 | 0.80 | CA12 (0.38) | CA2CA12CA14DGAT1MAOA | |
| SCHEMBL1278083 | 0.79 | CA12 (0.35) | CA2CA12CA14DGAT1MAOA | |
| SCHEMBL25960668 | 0.79 | CYP1A2 (0.38) | CA2CA12CA14DGAT1MAOA | |
| SCHEMBL19876856 | 0.79 | EPHX2 (0.36) | CA2CA12CA14DGAT1MAOA | |
| SCHEMBL397677 | 0.78 | CA2 (0.37) | CA2CA12CA14DGAT1MAOA | |
| SCHEMBL1841358 | 0.78 | LATS1 (0.37) | CA2CA12CA14DGAT1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805367-B | Triazole pyrimidine derivative and preparation method and application thereof | 郑州大学 | 2023-04-07 | — | — | CN | claimed |
| CN-114805367-A | Triazole pyrimidine derivative and preparation method and application thereof | 郑州大学 | 2022-07-29 | — | — | CN | claimed |
| CN-114805367-B | Triazole pyrimidine derivative and preparation method and application thereof | 郑州大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-111615662-B | Liquid crystal aligning agent and polymer | JSR株式会社 | 2023-03-14 | — | — | CN | disclosed |
| CN-114805367-A | Triazole pyrimidine derivative and preparation method and application thereof | 郑州大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-111615662-A | Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal element, polymer and compound | JSR株式会社 | 2020-09-01 | — | — | CN | disclosed |
| WO-2019202853-A1 | LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, LIQUID CRYSTAL ELEMENT, POLYMER AND COMPOUND | JSR株式会社 | 2019-10-24 | — | — | WO | disclosed |
| EP-2500340-A1 | 2-Cyanophenyl Sulfonamide Derivatives Useful as Pesticides | Syngenta Participations AG. (CH) | 2012-09-19 | — | — | EP | disclosed |
| US-20100311582-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-09 | — | — | US | disclosed |
| US-7244846-B2 | Substituted benzofuran-2-carboxamides derivatives | MERCK PATENT GMBH (DE) | 2007-07-17 | — | — | US | disclosed |
| US-20050075269-A1 | N-(2-methoxyethyl)-5-{4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl}benzofuran-2-carboxamide; serotonin receptor antagonists, treating depression, anxiety states, panic attacks, obsessive-compulsive disorders, psychiatric illnesses, cerebral infarction, cerebral ischaemia, anxiolytic agents | MERCK PATENT GMBH (DE) | 2005-04-07 | — | — | US | disclosed |
| EP-1368346-A1 | SUBSTITUTED BENZOFURAN-2-CARBOXAMIDES DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002083666-A1 | SUBSTITUTED BENZOFURAN-2-CARBOXAMIDES DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075269-A1 | N-(2-methoxyethyl)-5-{4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl}benzofuran-2-carboxamide; serotonin receptor antagonists, treating depression, anxiety states, panic attacks, obsessive-compulsive disorders, psychiatric illnesses, cerebral infarction, cerebral ischaemia, anxiolytic agents | NPY2R, HTR1A, NPY1R | CA2 4008/4885CA12 4618/4885CA14 4777/4885 |
| US-20100311582-A1 | CHEMICAL COMPOUNDS | CBR3, CBR1, CCNY | CA2 346/4885CA12 1252/4885CA14 2244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.