Biphenyl

Biphenyl

SCHEMBL377328

CP(=O)(O)O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 2/20 0.54
ALDH1A1 P00352 1/20 0.53
PTPN5 P54829 2/20 0.52
CA2 P00918 3/20 0.50
CA4 P22748 1/20 0.50
CA5A P35218 1/20 0.50
MMP8 P22894 2/20 0.48
MMP14 P50281 2/20 0.48
CA14 Q9ULX7 2/20 0.48
MAPT P10636 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
PTPN1 P18031 1/20 0.47
ESR1 P03372 1/20 0.46
MMP3 P08254 1/20 0.46
BCL2L1 Q07817 1/20 0.46
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
CTDSP1 Q9GZU7 1/20 0.44
SRC P12931 2/20 0.44
CFTR P13569 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL10731115 0.90 HPGD (0.48) ACP3ALDH1A1PTPN5MMP8MMP14
Biphenyl SCHEMBL3727875 0.88 ALDH1A1 (0.60) ACP3ALDH1A1PTPN5CA2CA4
Biphenyl SCHEMBL1945860 0.88 ALDH1A1 (0.60) ACP3ALDH1A1PTPN5CA2CA4
Biphenyl SCHEMBL342228 0.88 ALDH1A1 (0.60) ACP3ALDH1A1PTPN5CA2CA4
Biphenyl SCHEMBL27485598 0.88 ALDH1A1 (0.60) ACP3ALDH1A1PTPN5CA2CA4
Biphenyl SCHEMBL263925 0.88 ALDH1A1 (0.60) ACP3ALDH1A1PTPN5CA2CA4
Biphenyl SCHEMBL3763955 0.88 ALDH1A1 (0.60) ACP3ALDH1A1PTPN5CA2CA4
Biphenyl SCHEMBL27822260 0.86 ACP3 (0.52) ACP3ALDH1A1PTPN5CA2CA4
Biphenyl SCHEMBL11128267 0.85 ALDH1A1 (0.56) ACP3ALDH1A1PTPN5CA2CA4
Biphenyl SCHEMBL356478 0.85 ALDH1A1 (0.56) ACP3ALDH1A1PTPN5CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2655383-A2 HYPERBRANCHED OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX Polymers, Inc. (US) 2013-10-30 EP claimed
EP-2655384-A2 OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX Polymers, Inc. (US) 2013-10-30 EP claimed
US-8563638-B2 Oligomeric phosphonates and compositions including the same FRX POLYMERS, INC. (US) 2013-10-22 US claimed
CN-103328702-A Phosphonate polymers, copolymers and respective oligomers thereof as flame retardants for polyester fibers FRX POLYMERS INC 2013-09-25 CN claimed
US-8530044-B2 Hyperbranched oligomeric phosphonates and compositions including the same FRX POLYMERS, INC. (US) 2013-09-10 US claimed
US-20120171460-A1 HYPERBRANCHED OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX POLYMERS, INC. (US) 2012-07-05 US claimed
US-20120172500-A1 OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX POLYMERS, INC. (US) 2012-07-05 US claimed
WO-2012088406-A2 OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX POLYMERS, INC. (US) 2012-06-28 WO claimed
WO-2012088435-A2 HYPERBRANCHED OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX POLYMERS, INC. (US) 2012-06-28 WO claimed
US-10435508-B2 Flame-retardant resin composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2019-10-08 US disclosed
CN-110300757-A With phosphonate oligomers cured epoxy resin FRX 聚合物股份有限公司 2019-10-01 CN disclosed
CN-109971144-A Polyphosphonates and copolymerization phosphonate additives mixture FRX 聚合物股份有限公司 2019-07-05 CN disclosed
CN-103351583-B The polymer blend and its product for including cyclobutanediol with certain of logarithmic viscosity number and medium glass transition temperature combination 伊士曼化工公司 2018-08-28 CN disclosed
CN-108264768-A A kind of halogen-free fire-resistant engineering plastics polysulfones 五邑大学 2018-07-10 CN disclosed
CN-1988951-A Method and device for the gradual production of polymers using melt condensation ZIMMER AG (DE) 2007-06-27 CN disclosed
US-20050253115-A1 Heat-resistant exfoliated graphite sheet OILES CORPORATION (JP) 2005-11-17 US disclosed
EP-1559680-A1 HEAT-RESISTANT EXFOLIATED GRAPHITE SHEET Oiles Corporation (JP) 2005-08-03 EP disclosed
EP-0736539-B1 Mesoporous crystalline acid composition of a diphosphonate-phosphite of a tetravalent metal which can be used as a catalyst ENITECNOLOGIE SPA (IT) 2000-12-20 EP disclosed
US-5892080-A Mesoporous crystalline acid composition of a diphosphonate-phosphite of a tetravalent metal which can be used as a catalyst ENIRICERCHE S.P.A. (IT) 1999-04-06 US disclosed
EP-0736539-A2 Mesoporous crystalline acid composition of a diphosphonate-phosphite of a tetravalent metal which can be used as a catalyst ENIRICERCHE S.p.A. (IT) 1996-10-09 EP disclosed