Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CBLB | Q13191 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1401179 | 1.00 | PLA2G2A (0.36) | PLA2G2AADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL1401053 | 0.92 | PLA2G2A (0.36) | PLA2G2AALDH1A1LMNACBLB | |
| SCHEMBL3780082 | 0.91 | ABCG2 (0.36) | PLA2G2AALDH1A1LMNACBLB | |
| SCHEMBL3779589 | 0.91 | PLA2G2A (0.36) | PLA2G2A | |
| SCHEMBL5493627 | 0.90 | POLB (0.38) | — | |
| SCHEMBL3809767 | 0.82 | CYSLTR1 (0.41) | PLA2G2AALDH1A1LMNA | |
| SCHEMBL3773865 | 0.81 | PLA2G2A (0.41) | PLA2G2AALDH1A1LMNA | |
| SCHEMBL1401054 | 0.81 | PLA2G2A (0.38) | PLA2G2AALDH1A1LMNACBLB | |
| SCHEMBL1401180 | 0.81 | PLA2G2A (0.38) | PLA2G2AALDH1A1CBLB | |
| SCHEMBL12927207 | 0.81 | PLA2G2A (0.50) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812393-B1 | METHYL 2-[(3S)-[3-[(2E)-(7-CHLOROQUINOLIN-2-YL) ETHENYL]PHENYL]-3-HALOPROPYL]-BENZOATE ESTER | MATRIX LAB LTD (IN) | 2011-12-28 | — | — | EP | claimed |
| US-7858793-B2 | Methyl 2-[(3S)-[3-[2E)-(7-chloro quinolin-2-yl) ethenyl] phenyl]-3-halopropyl] benzoates | SATYANARAYANA CHAVA | 2010-12-28 | — | — | US | claimed |