Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809767 | 0.86 | CYSLTR1 (0.41) | PLA2G2AALDH1A1LMNACNR1MAPT | |
| SCHEMBL5816742 | 0.82 | ALDH1A1 (0.46) | PLA2G2AALDH1A1LMNAABCG2KDM4E | |
| SCHEMBL3773863 | 0.81 | PLA2G2A (0.36) | PLA2G2AALDH1A1LMNA | |
| SCHEMBL1401179 | 0.81 | PLA2G2A (0.36) | PLA2G2AALDH1A1LMNA | |
| SCHEMBL1401053 | 0.81 | PLA2G2A (0.36) | PLA2G2AALDH1A1LMNA | |
| SCHEMBL3779589 | 0.81 | PLA2G2A (0.36) | PLA2G2A | |
| SCHEMBL3780082 | 0.81 | ABCG2 (0.36) | PLA2G2AALDH1A1LMNAABCG2 | |
| SCHEMBL3809770 | 0.80 | PLA2G2A (0.39) | PLA2G2AALDH1A1ABCG2KDM4ECNR1 | |
| SCHEMBL1401180 | 0.78 | PLA2G2A (0.38) | PLA2G2AALDH1A1ABCG2KDM4ECNR1 | |
| SCHEMBL4957637 | 0.77 | MAPT (0.44) | PLA2G2AALDH1A1LMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858793-B2 | Methyl 2-[(3S)-[3-[2E)-(7-chloro quinolin-2-yl) ethenyl] phenyl]-3-halopropyl] benzoates | SATYANARAYANA CHAVA | 2010-12-28 | — | — | US | claimed |