Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.35 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12887140 | 0.89 | ALOX5 (0.36) | GPR35ALOX5TYRMEN1TP53 | |
| SCHEMBL2363742 | 0.87 | ALOX5 (0.41) | GPR35ALOX5TYRMEN1TP53 | |
| SCHEMBL4584517 | 0.87 | ALOX5 (0.41) | GPR35ALOX5TYRMEN1TP53 | |
| SCHEMBL2308334 | 0.87 | ALOX5 (0.41) | GPR35ALOX5TYRMEN1TP53 | |
| SCHEMBL15724614 | 0.86 | ALOX5 (0.39) | GPR35ALOX5TYRMEN1TP53 | |
| SCHEMBL15247276 | 0.85 | ALOX5 (0.33) | GPR35ALOX5TYRMEN1TP53 | |
| SCHEMBL15724617 | 0.85 | ALOX5 (0.36) | GPR35ALOX5TYRMEN1TP53 | |
| SCHEMBL27510160 | 0.85 | ALOX5 (0.38) | GPR35ALOX5TYRMEN1TP53 | |
| SCHEMBL10021733 | 0.84 | ALOX5 (0.38) | GPR35ALOX5TYRMEN1TP53 | |
| SCHEMBL2971213 | 0.84 | ALOX5 (0.38) | GPR35ALOX5TYRMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329915-B2 | Thienothiophene derivatives | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-12-11 | — | — | US | disclosed |
| US-8329915-B2 | Thienothiophene derivatives | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-12-11 | — | — | US | disclosed |
| US-20100331550-A1 | THIENOTHIOPHENE DERIVATIVES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2010-12-30 | — | — | US | disclosed |
| US-20100331550-A1 | THIENOTHIOPHENE DERIVATIVES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331550-A1 | THIENOTHIOPHENE DERIVATIVES | TST, TPST2, TH | GPR35 949/4885ALOX5 872/4885TYR 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.