Gamma-Aminobutyric Acid

Gamma-Aminobutyric Acid

SCHEMBL377444

NCCCC(=O)[O-].NCCCC(=O)[O-].[Zn+2]

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 3/20 0.52
HDAC1 Q13547 3/20 0.52
HDAC2 Q92769 3/20 0.52
HDAC8 Q9BY41 3/20 0.52
LMNA P02545 3/20 0.52
BLM P54132 3/20 0.52
THRB P10828 2/20 0.52
KMT2A Q03164 2/20 0.52
NPSR1 Q6W5P4 2/20 0.52
CYP1A2 P05177 2/20 0.52
GABRR3 A8MPY1 1/20 0.52
GABRP O00591 1/20 0.52
GABRD O14764 1/20 0.52
GABBR2 O75899 1/20 0.52
GABRA1 P14867 1/20 0.52
TSHR P16473 1/20 0.52
GABRB1 P18505 1/20 0.52
GABRG2 P18507 1/20 0.52
GABRR1 P24046 1/20 0.52
GABRB3 P28472 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gamma-Aminobutyric Acid SCHEMBL587529 0.94 HDAC3 (0.52) HDAC3HDAC1HDAC2HDAC8LMNA
Gamma-Aminobutyric Acid SCHEMBL2768668 0.94
Gamma-Aminobutyric Acid SCHEMBL28332521 0.94 HDAC3 (0.52) HDAC3HDAC1HDAC2HDAC8LMNA
Gamma-Aminobutyric Acid SCHEMBL587045 0.94 HDAC3 (0.52) HDAC3HDAC1HDAC2HDAC8LMNA
Gamma-Aminobutyric Acid SCHEMBL28879139 0.94 HDAC3 (0.52) HDAC3HDAC1HDAC2HDAC8LMNA
Gamma-Aminobutyric Acid SCHEMBL16177043 0.94
Gamma-Aminobutyric Acid SCHEMBL1685715 0.94
Gamma-Aminobutyric Acid SCHEMBL9283723 0.94
Gamma-Aminobutyric Acid SCHEMBL28332520 0.94
Aminocaproic Acid SCHEMBL28448259 0.89 LMNA (0.56) LMNABLMTHRBKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118160928-A Composition for promoting water supplementing and preparation method and application thereof 南京盛德创赢生物科技有限公司 2024-06-11 CN claimed
CN-111377775-A Active synergistic fertilizer special for corn 黑龙江农垦乾源肥业有限公司 2020-07-07 CN claimed
CN-118160928-A Composition for promoting water supplementing and preparation method and application thereof 南京盛德创赢生物科技有限公司 2024-06-11 CN disclosed
CN-111377775-A Active synergistic fertilizer special for corn 黑龙江农垦乾源肥业有限公司 2020-07-07 CN disclosed
EP-2408722-A1 COATED SUBSTRATE UNIVERSITY COLLEGE LONDON (GB) 2012-01-25 EP disclosed
WO-2010106370-A1 COATED SUBSTRATE UNIVERSITY COLLEGE LONDON (GB) 2010-09-23 WO disclosed