Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Gamma-Aminobutyric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP known ✓ | O00591 | 1/20 | 0.52 |
| ▸ | GABRD known ✓ | O14764 | 1/20 | 0.52 |
| ▸ | GABBR2 known ✓ | O75899 | 1/20 | 0.52 |
| ▸ | GABRA1 known ✓ | P14867 | 1/20 | 0.52 |
| ▸ | GABRB1 known ✓ | P18505 | 1/20 | 0.52 |
| ▸ | GABRG2 known ✓ | P18507 | 1/20 | 0.52 |
| ▸ | GABRB3 known ✓ | P28472 | 1/20 | 0.52 |
| ▸ | GABRA5 known ✓ | P31644 | 1/20 | 0.52 |
| ▸ | GABRA3 known ✓ | P34903 | 1/20 | 0.52 |
| ▸ | GABRA2 known ✓ | P47869 | 1/20 | 0.52 |
| ▸ | GABRB2 known ✓ | P47870 | 1/20 | 0.52 |
| ▸ | GABRA4 known ✓ | P48169 | 1/20 | 0.52 |
| ▸ | GABRE known ✓ | P78334 | 1/20 | 0.52 |
| ▸ | GABRA6 known ✓ | Q16445 | 1/20 | 0.52 |
| ▸ | GABRG1 known ✓ | Q8N1C3 | 1/20 | 0.52 |
| ▸ | GABRG3 known ✓ | Q99928 | 1/20 | 0.52 |
| ▸ | GABBR1 known ✓ | Q9UBS5 | 1/20 | 0.52 |
| ▸ | GABRQ known ✓ | Q9UN88 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gamma-Aminobutyric Acid SCHEMBL7770294 | 0.95 | HDAC3 (0.48) | HDAC3HDAC1HDAC2HDAC8LMNA | |
| Gamma-Aminobutyric Acid SCHEMBL28332520 | 0.94 | — | — | |
| Gamma-Aminobutyric Acid SCHEMBL16177043 | 0.94 | — | — | |
| Gamma-Aminobutyric Acid SCHEMBL377444 | 0.94 | HDAC3 (0.52) | HDAC3HDAC1HDAC2HDAC8LMNA | |
| Gamma-Aminobutyric Acid SCHEMBL587045 | 0.94 | HDAC3 (0.52) | HDAC3HDAC1HDAC2HDAC8LMNA | |
| Gamma-Aminobutyric Acid SCHEMBL28879139 | 0.94 | HDAC3 (0.52) | HDAC3HDAC1HDAC2HDAC8LMNA | |
| Gamma-Aminobutyric Acid SCHEMBL9283723 | 0.94 | — | — | |
| Gamma-Aminobutyric Acid SCHEMBL1685715 | 0.94 | — | — | |
| Gamma-Aminobutyric Acid SCHEMBL28332521 | 0.94 | HDAC3 (0.52) | HDAC3HDAC1HDAC2HDAC8LMNA | |
| Gamma-Aminobutyric Acid SCHEMBL2768668 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122056386-A | Moisture absorption resistant slow release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122030612-A | Shear-resistant slow-release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-118978451-A | Preparation method of calcium tripdioate | 苏州满元生物科技有限公司 | 2024-11-19 | — | — | CN | claimed |
| CN-118160928-A | Composition for promoting water supplementing and preparation method and application thereof | 南京盛德创赢生物科技有限公司 | 2024-06-11 | — | — | CN | claimed |
| US-20180161365-A1 | Phosphate-Binding Magnesium Salts And Uses Thereof | CURRAX PHARMACEUTICALS LLC | 2018-06-14 | — | — | US | claimed |
| US-9889157-B2 | Phosphate-binding magnesium salts and uses thereof | CYPRESS PHARMACEUTICALS, INC. (US) | 2018-02-13 | — | — | US | claimed |
| US-20170202875-A1 | Phosphate-Binding Magnesium Salts And Uses Thereof | WILMINGTON SAVINGS FUND SOCIETY, FSB | 2017-07-20 | — | — | US | claimed |
| US-9610267-B2 | Phosphate-binding magnesium salts and uses thereof | CYPRESS PHARMACEUTICALS, INC. (US) | 2017-04-04 | — | — | US | claimed |
| US-20160256420-A1 | Phosphate-Binding Magnesium Salts And Uses Thereof | WILMINGTON SAVINGS FUND SOCIETY, FSB | 2016-09-08 | — | — | US | claimed |
| US-9339481-B2 | Phosphate-binding magnesium salts and uses thereof | CYPRESS PHARMACEUTICALS, INC. (US) | 2016-05-17 | — | — | US | claimed |
| EP-2416786-A1 | PHOSPHATE-BINDING MAGNESIUM SALTS AND USES THEREOF | Cypress Pharmaceutical, Inc. (US) | 2012-02-15 | — | — | EP | claimed |
| WO-2010117370-A1 | PHOSPHATE-BINDING MAGNESIUM SALTS AND USES THEREOF | CYPRESS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | claimed |
| US-20090269399-A1 | PHOSPHATE-BINDING MAGNESIUM SALTS AND USES THEREOF | CYPRESS PHARMACEUTICAL, INC. (US) | 2009-10-29 | — | — | US | claimed |
| JP-58065255-A | — | — | None | — | — | JP | disclosed |
| CN-122056386-A | Moisture absorption resistant slow release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-122030612-A | Shear-resistant slow-release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-15 | — | — | CN | disclosed |
| EP-0170933-B1 | GAMMA-AMINOBUTYRIC ACID DERIVATIVES, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | KURARAY CO., LTD. (JP) | 1988-08-31 | — | — | EP | disclosed |
| US-4703061-A | MEMORY IMPEDIMENT; BRAIN METABOLISM DYSFUNCTION | KURARAY CO., LTD. (JP) | 1987-10-27 | — | — | US | disclosed |
| EP-0170933-A1 | Gamma-aminobutyric acid derivatives, process for production thereof, and use thereof as medicaments | KURARAY CO., LTD. (JP) | 1986-02-12 | — | — | EP | disclosed |
| JP-S5865255-A | PREPARATION OF CALCIUM GAMMA-AMINOBUTYRATE | TANABE SEIYAKU CO LTD | 1983-04-18 | — | — | JP | disclosed |