SCHEMBL377474

SCHEMBL377474

C=C1C=CC(C(C)CC(=O)C=C(C)C)CC1

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.45
STAT3 P40763 1/20 0.38
ACLY P53396 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29756085 1.00 PTPN1 (0.45) PTPN1STAT3ACLY
SCHEMBL377306 1.00 PTPN1 (0.45) PTPN1STAT3ACLY
SCHEMBL21757939 0.78 PTPN1 (0.40) PTPN1STAT3
SCHEMBL30455949 0.78 PTPN1 (0.40) PTPN1STAT3
SCHEMBL158316 0.75 NR1I2 (0.37) PTPN1
SCHEMBL29349988 0.75 NR1I2 (0.37) PTPN1
SCHEMBL29456643 0.75 NR1I2 (0.37) PTPN1
SCHEMBL13767028 0.74 STAT3 (0.38) PTPN1STAT3
SCHEMBL19117757 0.74 STAT3 (0.41) PTPN1STAT3
SCHEMBL3092052 0.74 STAT3 (0.41) PTPN1STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4674283-A1 A COMPOSITION FOR IMPARTING A CURED MEAT APPEARANCE AND/OR FLAVOUR Kerry Group Services International Limited (IE) 2026-01-07 EP claimed
WO-2025090057-A1 ENCAPSULATION OF INSECTICIDES INTO BIOPOLYMER CAPSULES UNM RAINFOREST INNOVATIONS (US) 2025-05-01 WO claimed
US-20240238219-A1 CURCUMIN AND TURMERONE COMPOSITIONS & METHODS OF USE THEREOF CAVALERI HEALTH, INC. (CA) 2024-07-18 US claimed
US-20240081341-A1 ENCAPSULATION OF INSECTICIDES INTO BIOPOLYMER CAPSULES FUNDACAO OSWALDO CRUZ (BR) 2024-03-14 US claimed
US-20230321177-A1 POLYPHARMACEUTICAL DRUG COMPOSITIONS AND RELATED METHODS AVETA BIOMICS, INC. 2023-10-12 US claimed
EP-3773654-B1 POLYPHARMACEUTICAL DRUG COMPOSITIONS AND RELATED METHODS AVETA BIOMICS INC (US) 2023-09-20 EP claimed
US-11701402-B2 Polypharmaceutical drug compositions and related methods AVETA BIOMICS, INC. (US) 2023-07-18 US claimed
US-20220408729-A1 COMPOSITIONS CONTAINING METALLIC COMPOUNDS FOR PROLONGED DISINFECTION OF SURFACES AND THEIR USES NANOMATERIALES QUIMICOS AVANZADOS, S.A. DE C.V. (MX) 2022-12-29 US claimed
WO-2022229784-A1 MIXTURES OF EMULSIFIED TERPENES HAVING ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY VILLAGOMEZ DIAZ, Jennifer Paulina (EC) 2022-11-03 WO claimed
US-20220193177-A1 METHODS AND COMPOSITIONS FOR TREATING DYSBIOSIS OF ORAL MICROBIOME AVETA BIOMICS, INC. 2022-06-23 US claimed
WO-2013004740-A1 ANTICONVULSANT ACTIVITY OF TURMERIC OIL AND BISABOLENE SESQUITERPENOIDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2013-01-10 WO claimed
WO-2010062260-A1 VIRUS AND TARGET CELL INTERACTION INHIBITION THE THAILAND RESEARCH FUND (TH) 2010-06-03 WO claimed
EP-1453528-B1 COMPOSITIONS CONTAINING CURCUMA EXTRACTS FOR THE TREATMENT OF NEUROCEREBROVASCULAR DISORDERS COUNCIL SCIENT IND RES (IN) 2009-07-22 EP claimed
CN-101400359-A Extracts and methods comprising curcuma species HERBALSCIENCE SINGAPORE PTE LTD (US) 2009-04-01 CN claimed
EP-2010199-A2 EXTRACTS AND METHODS COMPRISING CURCUMA SPECIES Herbalscience Singapore Pte. Ltd. (US) 2009-01-07 EP claimed
US-20080312333-A1 Agent for Preventing/Ameliorating Life Style-Related Diseases Containing Turmeric Essential Oil Component KANEKA CORPORATION (JP) 2008-12-18 US claimed
US-20080193573-A1 Extracts and methods comprising curcuma species HERBALSCIENCE SINGAPORE PTE. LTD. (SG) 2008-08-14 US claimed
WO-2007109210-A2 EXTRACTS AND METHODS COMPRISING CURCUMA SPECIES HERBALSCIENCE SINGAPORE PTE. LTD. (US) 2007-09-27 WO claimed
CN-1956713-A Agent for preventing/amelioration life style-related diseases containing turmeric essential oil component KANEGAFUCHI CHEMICAL IND (JP) 2007-05-02 CN claimed
EP-1752144-A1 AGENT FOR PREVENTING/AMELIORATIG LIFE STYLE-RELAETD DISEASES CONTAINING TURMERIC ESSENTIAL OIL COMPONENT Kaneka Corporation (JP) 2007-02-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238219-A1 CURCUMIN AND TURMERONE COMPOSITIONS & METHODS OF USE THEREOF NTRK2, MINK1, CAMKK2 PTPN1 2612/4885STAT3 787/4885ACLY 2774/4885
US-11701402-B2 Polypharmaceutical drug compositions and related methods PCBP1, CYP3A5, ABCB1 PTPN1 3815/4885STAT3 2934/4885ACLY 2233/4885
US-20220193177-A1 METHODS AND COMPOSITIONS FOR TREATING DYSBIOSIS OF ORAL MICROBIOME NOP2, LPO, UNG PTPN1 2991/4885STAT3 2883/4885ACLY 719/4885
US-20080193573-A1 Extracts and methods comprising curcuma species APP, BACE1, PSEN1 PTPN1 4826/4885STAT3 3319/4885ACLY 1631/4885
US-20230321177-A1 POLYPHARMACEUTICAL DRUG COMPOSITIONS AND RELATED METHODS PCBP1, CYP3A5, ABCB1 PTPN1 3815/4885STAT3 2934/4885ACLY 2233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.