Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20773998 | 0.92 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 | |
| SCHEMBL2273812 | 0.91 | GSTP1 (0.44) | CYP1A2MCL1ACMSDEDNRBEDNRA | |
| SCHEMBL3777907 | 0.91 | ALDH1A1 (0.42) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 | |
| SCHEMBL20774101 | 0.88 | HPRT1 (0.42) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 | |
| SCHEMBL20774179 | 0.86 | HPRT1 (0.44) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 | |
| SCHEMBL20774140 | 0.85 | HPRT1 (0.50) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 | |
| SCHEMBL28619356 | 0.84 | HPRT1 (0.39) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 | |
| SCHEMBL20774118 | 0.83 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 | |
| SCHEMBL2267278 | 0.83 | MCL1 (0.44) | ALDH1A1HSD17B10CYP1A2MCL1ACMSD | |
| SCHEMBL20774189 | 0.83 | ALDH1A1 (0.44) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094223-B | binaphthyl compounds | 罗伊特化学仪器制造公司 | 2023-10-27 | — | — | CN | disclosed |
| US-11072573-B2 | Binaphthyl compounds | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2021-07-27 | — | — | US | disclosed |
| US-20200354299-A1 | BINAPHTHYL COMPOUNDS | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2020-11-12 | — | — | US | disclosed |
| EP-3676239-A1 | BINAPHTHYL COMPOUNDS | Reuter Chemische Apparatenbau e.K. (DE) | 2020-07-08 | — | — | EP | disclosed |
| CN-111094223-A | Binaphthyl compounds | 罗伊特化学仪器制造公司 | 2020-05-01 | — | — | CN | disclosed |
| WO-2019043060-A1 | BINAPHTHYL COMPOUNDS | REUTER CHEMISCHE APPARATEBAU KG (DE) | 2019-03-07 | — | — | WO | disclosed |
| US-8568903-B2 | Phenanthrene derivative, and material for organic EL element | IDEMITSU KOSAN CO., LTD. (JP) | 2013-10-29 | — | — | US | disclosed |
| US-20100327230-A1 | PHENANTHRENE DERIVATIVE, AND MATERIAL FOR ORGANIC EL ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354299-A1 | BINAPHTHYL COMPOUNDS | UACA, C9, C1S | ALDH1A1 1476/4885HSD17B10 1245/4885HIF1A 2959/4885 |
| US-20100327230-A1 | PHENANTHRENE DERIVATIVE, AND MATERIAL FOR ORGANIC EL ELEMENT | LEF1, AR, NR0B1 | ALDH1A1 1250/4885HSD17B10 2313/4885HIF1A 1972/4885 |
| US-11072573-B2 | Binaphthyl compounds | UACA, C9, C1S | ALDH1A1 1476/4885HSD17B10 1245/4885HIF1A 2959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.