Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.52 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.52 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30822033 | 1.00 | MAPK1 (0.55) | MAPK1MAPTGAAALDH1A1TSHR | |
| SCHEMBL4416018 | 0.87 | MAPK1 (0.57) | MAPK1MAPTGAAALDH1A1TSHR | |
| SCHEMBL29910964 | 0.85 | MAPT (0.50) | MAPK1MAPTGAAALDH1A1TSHR | |
| SCHEMBL6690245 | 0.85 | MAPT (0.50) | MAPK1MAPTGAAALDH1A1TSHR | |
| SCHEMBL11173503 | 0.84 | MEN1 (0.47) | MAPK1MAPTGAAALDH1A1TSHR | |
| SCHEMBL30934663 | 0.84 | MEN1 (0.47) | MAPK1MAPTGAAALDH1A1TSHR | |
| SCHEMBL29942185 | 0.84 | ALDH1A1 (0.60) | MAPK1MAPTGAAALDH1A1TSHR | |
| SCHEMBL7240751 | 0.84 | ALDH1A1 (0.60) | MAPK1MAPTGAAALDH1A1TSHR | |
| SCHEMBL27705161 | 0.84 | TSHR (0.51) | MAPK1MAPTALDH1A1TSHRCYP3A4 | |
| SCHEMBL550419 | 0.83 | TSHR (0.44) | MAPK1MAPTGAAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4712967-A2 | G-PROTEIN COUPLED RECEPTOR ANTAGONIST | Enveda Therapeutics, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| US-20250326777-A1 | COMPOUNDS, COMPOSITIONS AND METHODS THEREOF | HEPAITECH BEIJING BIOPHARMA TECH CO LTD (CN) | 2025-10-23 | — | — | US | disclosed |
| WO-2024239000-A2 | G-PROTEIN COUPLED RECEPTOR ANTAGONIST | ENVEDA THERAPEUTICS, INC. (US) | 2024-11-21 | — | — | WO | disclosed |
| US-20230225201-A1 | Organic Light Emitting Diode and Device Comprising the Same | NOVALED GMBH (DE) | 2023-07-13 | — | — | US | disclosed |
| CN-113387823-B | Anthranilic acid and derivative thereof, and synthetic method and application thereof | 华东师范大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-113387823-A | Anthranilic acid and derivative thereof, and synthetic method and application thereof | 华东师范大学 | 2021-09-14 | — | — | CN | disclosed |
| CN-107207466-B | Bicyclic compounds as pest control agents | 拜耳作物科学股份公司 | 2020-09-08 | — | — | CN | disclosed |
| EP-3227274-B1 | BICYCLIC COMPOUNDS AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2019-07-03 | — | — | EP | disclosed |
| EP-3052495-B1 | NOVEL BICYCLIC PYRIDINONES AS GAMMA-SECRETASE MODULATORS | PFIZER (US) | 2019-06-26 | — | — | EP | disclosed |
| US-10131649-B2 | Bicyclic compounds as pest control agents | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-11-20 | — | — | US | disclosed |
| EP-0129528-A1 | Process for the preparation of nitro-substituted benzotrifluoride compounds | MONSANTO COMPANY (US) | 1984-12-27 | — | — | EP | disclosed |
| US-4467125-A | HERBICIDES | MONSANTO COMPANY (US) | 1984-08-21 | — | — | US | disclosed |
| US-4388472-A | Substituted diphenyl ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-06-14 | — | — | US | disclosed |
| EP-0023100-B1 | HERBICIDAL COMPOSITIONS COMPRISING A DIPHENYL ETHER COMPOUND IN ADMIXTURE WITH ANOTHER HERBICIDE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-11-10 | — | — | EP | disclosed |
| EP-0023100-A1 | Herbicidal compositions comprising a diphenyl ether compound in admixture with another herbicide | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-01-28 | — | — | EP | disclosed |
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |
| US-4132737-A | ENZYME INHIBITORS | ELI LILLY AND COMPANY (US) | 1979-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10131649-B2 | Bicyclic compounds as pest control agents | DDT, BCHE, BAK1 | MAPK1 3503/4885MAPT 3026/4885GAA 2397/4885 |
| US-20250326777-A1 | COMPOUNDS, COMPOSITIONS AND METHODS THEREOF | MRGPRX4, MRGPRX1, MRGPRX2 | MAPK1 2603/4885MAPT 2953/4885GAA 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.