Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.60 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.60 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPD | P32754 | 2/20 | 0.50 |
| ▸ | MASP2 | O00187 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29942185 | 1.00 | ALDH1A1 (0.60) | ALDH1A1CYP3A4TSHRHPGDALOX15 | |
| SCHEMBL113070 | 0.84 | TDP1 (0.60) | ALDH1A1CYP3A4TSHRHPGDALOX15 | |
| SCHEMBL29398386 | 0.84 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TSHRHPGDALOX15 | |
| SCHEMBL30822033 | 0.84 | MAPK1 (0.55) | ALDH1A1CYP3A4TSHRHPGDALOX15 | |
| SCHEMBL3778792 | 0.84 | MAPK1 (0.55) | ALDH1A1CYP3A4TSHRHPGDALOX15 | |
| SCHEMBL1995690 | 0.84 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TSHRHPGDALOX15 | |
| SCHEMBL1998640 | 0.84 | CYP3A4 (0.52) | ALDH1A1CYP3A4TSHRHPGDALOX15 | |
| SCHEMBL11668743 | 0.84 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TSHRHPGDALOX15 | |
| SCHEMBL2158306 | 0.84 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TSHRHPGDALOX15 | |
| SCHEMBL5961 | 0.84 | ALDH1A1 (0.58) | ALDH1A1CYP3A4TSHRHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206332-A | A kind of preparation method and application of flumetralim haptens and antigen | 中国烟草总公司郑州烟草研究院 | 2019-01-15 | — | — | CN | claimed |
| CN-109061171-A | It is a kind of detect flumetralim enzyme linked immunological kit and its application | 中国烟草总公司郑州烟草研究院 | 2018-12-21 | — | — | CN | claimed |
| CN-109641889-A | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | 百欧伊米克思有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-109206332-A | A kind of preparation method and application of flumetralim haptens and antigen | 中国烟草总公司郑州烟草研究院 | 2019-01-15 | — | — | CN | disclosed |
| CN-103827116-B | As LP-PLA2the 2,3-glyoxalidine of inhibitor also [1,2-c] pyrimidine-5 (1H)-one compound | 葛兰素集团有限公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-103261170-B | Fused heterocyclic compounds and their use for pest control | 住友化学株式会社 | 2016-08-24 | — | — | CN | disclosed |
| EP-2739627-A1 | 2,3-DIHYDROIMIDAZO[1,2-C]PYRIMIDIN-5(1H)-ONE COMPOUNDS USE AS LP-PLA² INHIBITORS | Glaxo Group Limited (GB) | 2014-06-11 | — | — | EP | disclosed |
| CN-102256614-B | Synthetic mimetics of host defense and uses thereof | POLYMEDIX INC | 2014-01-08 | — | — | CN | disclosed |
| EP-2655337-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | Sumitomo Chemical Company Limited (JP) | 2013-10-30 | — | — | EP | disclosed |
| WO-2013013503-A1 | 2,3-DIHYDROIMIDAZO[1,2-C] PYRIMIDIN-5(1H)-ONE COMPOUNDS USE AS LP-PLA2 INHIBITORS | GLAXO GROUP LIMITED (GB) | 2013-01-31 | — | — | WO | disclosed |
| WO-2012086848-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-28 | — | — | WO | disclosed |
| CN-102323341-A | Method for detecting 18 varieties of protein hydrolytic amino acids in milk powder through high-performance liquid chromatographic method | SHANXI EXIT INSPECTION TECHNOLOGY CT OF INSPECTION AND QUARANTINE BUREAU | 2012-01-18 | — | — | CN | disclosed |
| CN-102256614-A | Synthetic mimetics of host defense and uses thereof | POLYMEDIX INC | 2011-11-23 | — | — | CN | disclosed |
| US-20030099910-A1 | PHOTOCHROMIC SPIROBENZOPYRAN COMPOUNDS AND THEIR DERIVATIVES, SPIROPYRAN GROUP-CONTAINING POLYMERS, PROCESS FOR PRODUCING THE SAME, COMPOSITIONS COMPRISING SAID SPIROPYRANS OR SPIROPYRAN GROUP-CONTAINING POLYMERS AND PHOTOCHROMIC SWITCH THIN FILMS PREPARED | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2003-05-29 | — | — | US | disclosed |
| CN-1037143-A | N-phenylbenzamaide class and N-phenylbenzylamine oximes, its preparation method contains the preparation of this two compounds and as the purposes of sterilant | HOECHST AG (DE) | 1989-11-15 | — | — | CN | disclosed |
| US-4520197-A | Tetrahydrobenzodiazaphosphorindiones and tetrahydropyridodiazaphosphorindiones | ZOECON CORPORATION (US) | 1985-05-28 | — | — | US | disclosed |
| US-4433149-A | Esters of ureido-phenyl (or pyridyl) phosphinic acids | ZOECON CORPORATION (US) | 1984-02-21 | — | — | US | disclosed |