Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Methionine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.55 |
| ▸ | BHMT | Q93088 | 10/20 | 0.52 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.52 |
| ▸ | NOS2 | P35228 | 3/20 | 0.47 |
| ▸ | NOS3 | P29474 | 2/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | GRM8 | O00222 | 1/20 | 0.45 |
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Racemethionine SCHEMBL377909 | 1.00 | RNPEP (0.55) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Racemethionine SCHEMBL29275085 | 0.98 | RNPEP (0.57) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Racemethionine SCHEMBL29275088 | 0.98 | RNPEP (0.57) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Methionine SCHEMBL38922 | 0.98 | RNPEP (0.57) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Racemethionine SCHEMBL29275087 | 0.98 | RNPEP (0.57) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Racemethionine SCHEMBL29275086 | 0.98 | RNPEP (0.57) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Racemethionine SCHEMBL38923 | 0.98 | RNPEP (0.57) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Racemethionine SCHEMBL3970073 | 0.98 | RNPEP (0.57) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Racemethionine SCHEMBL10879097 | 0.96 | RNPEP (0.55) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Methionine SCHEMBL8388172 | 0.96 | RNPEP (0.55) | RNPEPBHMTBHMT2NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173584-B2 | Composition and method for treating semiconductor substrate surface | LASERWORT LTD (HK) | 2012-05-08 | — | — | US | claimed |
| US-20120083436-A1 | COMPOSITION AND METHOD FOR TREATING SEMICONDUCTOR SUBSTRATE SURFACE | LASERWORT LTD (HK) | 2012-04-05 | — | — | US | claimed |
| US-8101561-B2 | Composition and method for treating semiconductor substrate surface | LASERWORT LTD (HK) | 2012-01-24 | — | — | US | claimed |
| US-20110118165-A1 | COMPOSITION AND METHOD FOR TREATING SEMICONDUCTOR SUBSTRATE SURFACE | Lee, Wai Mun (US) | 2011-05-19 | — | — | US | claimed |
| US-20260027162-A1 | MUCISPIRILLUM COMPOSITIONS AND CANCER TREATMENT METHODS THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2026-01-29 | — | — | US | disclosed |
| EP-4555326-A2 | MUCISPIRILLUM COMPOSITIONS AND CANCER TREATMENT METHODS THEREOF | President And Fellows Of Harvard College (US) | 2025-05-21 | — | — | EP | disclosed |
| WO-2024015955-A2 | MUCISPIRILLUM COMPOSITIONS AND CANCER TREATMENT METHODS THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-01-18 | — | — | WO | disclosed |
| US-20220264921-A1 | NOVEL FLAVOR COMPOSITION AND METHODS OF PREPARATION AND USES THEREOF | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2022-08-25 | — | — | US | disclosed |
| EP-3996524-A1 | NOVEL FLAVOR COMPOSITION AND METHODS OF PREPARATION AND USES THEREOF | International Flavors and Fragrances Inc. (US) | 2022-05-18 | — | — | EP | disclosed |
| WO-2021007476-A1 | NOVEL FLAVOR COMPOSITION AND METHODS OF PREPARATION AND USES THEREOF | INTERNATIONAL FLAVORS AND FRAGRANCES INC. (US) | 2021-01-14 | — | — | WO | disclosed |
| EP-2368945-B1 | CORROSION RESISTANT COATINGS | UNIV MISSOURI (US) | 2019-03-27 | — | — | EP | disclosed |
| US-8173584-B2 | Composition and method for treating semiconductor substrate surface | LASERWORT LTD (HK) | 2012-05-08 | — | — | US | disclosed |
| EP-1587884-A2 | CORROSION RESISTANT COATINGS CONTAINING RARE EARTH COMPOUNDS | University of Missouri Curators, Office of Tech. & Spec. Projects (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1587885-A2 | CORROSION RESISTANT COATINGS CONTAINING CARBON PIGMENTS | University of Missouri Curators, Office of Tech. & Spec. Projects (US) | 2005-10-26 | — | — | EP | disclosed |
| US-20040249043-A1 | Rare earth metals for coatings with acid extenders, magnesium sulfate, calcium sulfate, barium sulfate, strontium sulfate, samarium sulfate with inorganic polymers and metal oxides | CURATORS OF THE UNIVERSITY OF MISSOURI, THE | 2004-12-09 | — | — | US | disclosed |
| US-20040249023-A1 | Compounds for corrosion resistant primer coatings and protection of metal substrates | CURATORS OF THE UNIVERSITY OF MISSOURI, THE | 2004-12-09 | — | — | US | disclosed |
| WO-2004065498-A2 | CORROSION RESISTANT COATINGS CONTAINING CARBON PIGMENTS | UNIVERSITY OF MISSOURI CURATORS (US) | 2004-08-05 | — | — | WO | disclosed |
| WO-2004065497-A2 | CORROSION RESISTANT COATINGS CONTAINING RARE EARTH COMPOUNDS | UNIVERSITY OF MISSOURI CURATORS (US) | 2004-08-05 | — | — | WO | disclosed |
| US-4680283-A | LACHRYMATORS | MERCK & CO., INC. (US) | 1987-07-14 | — | — | US | disclosed |
| EP-0176436-A2 | Analogs of substance P and eledoisin | MERCK & CO. INC. (US) | 1986-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260027162-A1 | MUCISPIRILLUM COMPOSITIONS AND CANCER TREATMENT METHODS THEREOF | SAAL1, CD74, MUC1 | RNPEP 2914/4885BHMT 2019/4885BHMT2 1316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.