Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 4/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3776417 | 0.89 | CHRNB1 (0.41) | GSK3BCYP11B1CYP11B2GRIN2BPDK1 | |
| SCHEMBL3778997 | 0.86 | DGAT1 (0.36) | GSK3BCYP11B1CYP11B2GRIN2BDYRK1A | |
| SCHEMBL3779002 | 0.84 | CHRNB1 (0.37) | CYP11B2SLC22A12CLK1DYRK1ACHRNB1 | |
| SCHEMBL3775792 | 0.83 | CHRNB1 (0.41) | SLC22A12CHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3780627 | 0.82 | CYP11B2 (0.35) | CYP11B1CYP11B2SLC22A12CHRNB1CHRNB2 | |
| SCHEMBL3774462 | 0.81 | MAP4K4 (0.41) | GSK3BCYP11B1CYP11B2SLC22A12DYRK1A | |
| SCHEMBL3774126 | 0.80 | CNR2 (0.41) | MAPTGRIN2BSLC22A12 | |
| SCHEMBL3768294 | 0.80 | CHRNB1 (0.43) | CYP11B2GRIN2BDYRK1ACHRNB1CHRNB2 | |
| SCHEMBL3780596 | 0.80 | CTPS1 (0.34) | CYP11B1CYP11B2SLC22A12CHRNB1CHRNB2 | |
| SCHEMBL3151299 | 0.80 | ABL1 (0.37) | ABL1MAPTGSK3BCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317698-A1 | Polysubstituted Pyridinylaminoalkylene- and Pyridinyloxyalkylene-Cyclopropanamine Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them | LES LABORATOIRES SERVIER (FR) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317698-A1 | Polysubstituted Pyridinylaminoalkylene- and Pyridinyloxyalkylene-Cyclopropanamine Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them | CHRNA6, CHRNE, CHRNG | ABL1 1469/4885MAPT 3996/4885GSK3B 914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.