Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 8/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304609 | 0.86 | ITGA4 (0.39) | ACEITGB3ITGA2BITGA4ITGB7 | |
| SCHEMBL304610 | 0.86 | ITGA4 (0.39) | ACEITGB3ITGA2BITGA4ITGB7 | |
| SCHEMBL28622648 | 0.85 | PPARA (0.57) | ACEITGB3ITGA2BPPARAPPARG | |
| SCHEMBL28622647 | 0.85 | PPARA (0.57) | ACEITGB3ITGA2BPPARAPPARG | |
| SCHEMBL13259431 | 0.83 | TACR1 (0.52) | ACEPPARACTSSCTSKCTSL | |
| SCHEMBL1133305 | 0.82 | ITGB3 (0.48) | ACEITGB3ITGA2BPTPN1SCN9A | |
| SCHEMBL214303 | 0.82 | ITGB3 (0.48) | ACEITGB3ITGA2BPTPN1SCN9A | |
| SCHEMBL214302 | 0.82 | ITGB3 (0.48) | ACEITGB3ITGA2BPTPN1SCN9A | |
| SCHEMBL18681589 | 0.81 | CYP2D6 (0.40) | CTSSCTSK | |
| SCHEMBL29110986 | 0.79 | ACE (0.51) | ACEITGB3ITGA2BPTPN1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210882-A1 | Synthesis of new protected azahistidine, their processes and their use in synthesises | Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) | 2010-07-28 | — | — | EP | disclosed |
| WO-2010081882-A2 | SYNTHESIS OF NEW PROTECTED AZAHISTIDINES, THEIR PROCESSES AND THEIR USE IN SYNTHESISES | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2010-07-22 | — | — | WO | disclosed |