Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 2/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | DDX3X | O00571 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786374 | 0.92 | CYP17A1 (0.57) | CYP17A1MAP4K4ALDH1A1JAK2DDX3X | |
| SCHEMBL3784632 | 0.90 | CYP17A1 (0.47) | CYP17A1MAP4K4BRD4CREBBPHDAC1 | |
| SCHEMBL3793046 | 0.88 | MAP4K4 (0.58) | CYP17A1MAP4K4JAK2BRD4CREBBP | |
| SCHEMBL3781738 | 0.86 | MAP4K4 (0.50) | CYP17A1MAP4K4HDAC1HDAC3HDAC2 | |
| SCHEMBL656043 | 0.86 | ALDH1A1 (0.60) | CYP17A1MAP4K4ALDH1A1DDX3XBRD4 | |
| SCHEMBL29478358 | 0.86 | ALDH1A1 (0.60) | CYP17A1MAP4K4ALDH1A1DDX3XBRD4 | |
| SCHEMBL10305747 | 0.82 | MAP4K4 (0.46) | CYP17A1MAP4K4ALDH1A1HDAC1HDAC3 | |
| SCHEMBL3789848 | 0.82 | CYP17A1 (0.62) | CYP17A1MAP4K4BRD4CREBBPHDAC1 | |
| SCHEMBL3790360 | 0.82 | HDAC3 (0.41) | CYP17A1MAP4K4BRD4CREBBPHDAC1 | |
| SCHEMBL18391079 | 0.81 | ALDH1A1 (0.54) | CYP17A1MAP4K4ALDH1A1DDX3XBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | CYP17A1 179/4885MAP4K4 3704/4885ALDH1A1 4339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.