Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17007872 | 0.80 | HTT (0.59) | PDK1PDK2PDK3PDK4MAPK1 | |
| SCHEMBL3709926 | 0.80 | HTT (0.59) | PDK1PDK2PDK3PDK4MAPK1 | |
| SCHEMBL18361484 | 0.78 | GABRA1 (0.46) | ALDH1A1LMNAHTTHDAC3CYP2C9 | |
| SCHEMBL23381716 | 0.77 | ESR1 (0.51) | ALDH1A1HTTHDAC3CYP2C9HDAC1 | |
| SCHEMBL11529099 | 0.75 | HDAC3 (0.63) | LMNAHDAC3CYP2C9HDAC1HDAC6 | |
| SCHEMBL15760882 | 0.73 | GUCY1B2 (0.40) | ALDH1A1HTTHDAC3CYP2C9HDAC1 | |
| SCHEMBL17021753 | 0.73 | HDAC3 (0.38) | HTTHDAC3CYP2C9HDAC1HDAC6 | |
| SCHEMBL15760884 | 0.73 | GUCY1B2 (0.40) | ALDH1A1HTTHDAC3CYP2C9HDAC1 | |
| SCHEMBL3678697 | 0.73 | L3MBTL1 (0.43) | L3MBTL1MAPK1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3678695 | 0.73 | L3MBTL1 (0.43) | L3MBTL1MAPK1SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010084090-A1 | PYRIDYL-AZA(THIO)XANTHONE SENSITIZER COMPRISING LANTHANIDE(III) ION COMPLEXING COMPOUNDS, THEIR LUMINESCENT LANTHANIDE (III) ION COMPLEXES AND USE THEREOF AS FLUORESCENT LABELS. | CIS BIO INTERNATIONAL (FR) | 2010-07-29 | — | — | WO | disclosed |