Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEH1 | O60930 | 1/20 | 0.45 |
| ▸ | CCNE2 | O96020 | 7/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.40 |
| ▸ | CDK2 | P24941 | 7/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 6/20 | 0.40 |
| ▸ | CDK1 | P06493 | 6/20 | 0.40 |
| ▸ | CDK4 | P11802 | 6/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.40 |
| ▸ | CCND1 | P24385 | 6/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38295 | 0.88 | PDE5A (0.52) | CCNE2CCNE1CDK2CCNB2CDK1 | |
| SCHEMBL37467 | 0.84 | RNASEH1 (0.47) | RNASEH1CCNE2CCNE1CDK2CCNB2 | |
| SCHEMBL43863 | 0.78 | RNASEH1 (0.47) | RNASEH1CCNE2CCNE1CDK2CCNB2 | |
| SCHEMBL37727 | 0.78 | RNASEH1 (0.47) | RNASEH1CCNE2CCNE1CDK2CCNB2 | |
| SCHEMBL3492895 | 0.75 | RNASEH1 (0.51) | RNASEH1KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL3491664 | 0.75 | RNASEH1 (0.58) | RNASEH1KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL37850 | 0.75 | RNASEH1 (0.47) | RNASEH1CCNE2CCNE1CDK2CCNB2 | |
| SCHEMBL37998 | 0.74 | RNASEH1 (0.49) | RNASEH1CCNE2CCNE1CDK2CCNB2 | |
| SCHEMBL38887 | 0.74 | RNASEH1 (0.49) | RNASEH1CCNE2CCNE1CDK2CCNB2 | |
| SCHEMBL38376 | 0.74 | RNASEH1 (0.52) | RNASEH1KDM4EMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004900-A1 | THIENOPYRIMIDINE COMPOUNDS | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2012-01-12 | — | — | WO | disclosed |