Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7161621 | 0.88 | KDM4E (0.56) | LMNAKDM4ECYP3A4ACHEPOLB | |
| SCHEMBL6304659 | 0.84 | ACHE (0.59) | LMNAKDM4ECYP3A4ACHEPOLB | |
| SCHEMBL1846855 | 0.84 | MCL1 (0.57) | LMNAKDM4ECYP3A4ACHEMAPT | |
| SCHEMBL29001439 | 0.84 | KDM4E (0.61) | LMNAKDM4ECYP3A4ACHEPOLB | |
| SCHEMBL377507 | 0.84 | CYP3A4 (0.52) | LMNAKDM4ECYP3A4ACHEPOLB | |
| SCHEMBL27646258 | 0.84 | CYP3A4 (0.56) | LMNAKDM4ECYP3A4ACHEPOLB | |
| SCHEMBL9507367 | 0.84 | KDM4E (0.44) | LMNAKDM4EABCB11ALDH1A1KMO | |
| SCHEMBL9255310 | 0.83 | HSP90AA1 (0.48) | LMNAKDM4EALDH1A1KMOMEN1 | |
| SCHEMBL7001546 | 0.82 | ELANE (0.55) | LMNAKDM4EALDH1A1KMOHSP90AA1 | |
| SCHEMBL12316409 | 0.82 | LMNA (0.47) | LMNAKDM4ECYP3A4ABCB11ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071655-A1 | PROCESS FOR ENANTIOMERIC SEPARATION OF RACEMIC DIHYDRO-1,3,5, TRIAZINES VIA PREFERENTIAL CRYSTALLIZATION | POXEL (FR) | 2012-03-22 | — | — | US | claimed |
| EP-2411375-A1 | PROCESS FOR ENANTIOMERIC SEPARATION OF RACEMIC DIHYDRO-1,3,5 TRIAZINES VIA PREFERENTIAL CRYSTALLIZATION | Poxel (FR) | 2012-02-01 | — | — | EP | claimed |
| EP-2161992-B1 | ALKOXYLATED ASYMMETRIC ALKYLAMINE SURFACTANTS AS ADJUVANTS | AKZO NOBEL NV (NL) | 2010-11-17 | — | — | EP | claimed |
| WO-2010109015-A1 | PROCESS FOR ENANTIOMERIC SEPARATION OF RACEMIC DIHYDRO-1,3,5 TRIAZINES VIA PREFERENTIAL CRYSTALLIZATION | POXEL (FR) | 2010-09-30 | — | — | WO | claimed |
| EP-2161992-A1 | ALKOXYLATED ASYMMETRIC ALKYLAMINE SURFACTANTS AS ADJUVANTS | Akzo Nobel N.V. (NL) | 2010-03-17 | — | — | EP | claimed |
| WO-2009004044-A1 | ALKOXYLATED ASYMMETRIC ALKYLAMINE SURFACTANTS AS ADJUVANTS | AKZO NOBEL N.V. (NL) | 2009-01-08 | — | — | WO | claimed |
| US-4668276-A | FOR HERBICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-05-26 | — | — | US | claimed |
| CN-120121751-A | Method for detecting chlorophenols in waste gas and application thereof | 华电莱州发电有限公司 | 2025-06-10 | — | — | CN | disclosed |
| EP-4250925-A1 | LIQUID AGROCHEMICAL COMPOSITION | Nouryon Chemicals International B.V. (NL) | 2023-10-04 | — | — | EP | disclosed |
| CN-112063005-B | Preparation method of molecular imprinting integral needle type extraction device for enriching polychlorinated biphenyl | 吉林化工学院 | 2022-12-06 | — | — | CN | disclosed |
| US-20220324876-A1 | 4-SUBSTITUTED PYRANO[3,4,b]PYRAZINE KAPPA AGONISTS FOR TREATING DRUG DEPENDENCY | THE ROCKEFELLER UNIVERSITY | 2022-10-13 | — | — | US | disclosed |
| CN-114867350-A | Low volatility polyamine salts of anionic pesticides | 巴斯夫公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114727597-A | Methods of using compositions comprising anionic pesticides and buffers | 巴斯夫公司 | 2022-07-08 | — | — | CN | disclosed |
| US-4816465-A | Decahydroquinolines and analgesic use thereof | ROUSSEL UCLAF (FR) | 1989-03-28 | — | — | US | disclosed |
| EP-0162690-B1 | 2-OXA-SPIROCYCLIC-BENZENEACETAMIDES AND BENZAMIDES | THE UPJOHN COMPANY (US) | 1989-01-11 | — | — | EP | disclosed |
| CN-87100191-A | The hydroxy acid derivative of treatment diabetic complication | — | 1987-09-09 | — | — | CN | disclosed |
| WO-1987004344-A1 | HYDROXYACETIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETIC COMPLICATIONS | PFIZER INC. (US) | 1987-07-30 | — | — | WO | disclosed |
| EP-0230379-A2 | Chroman- and thiochroman-4-acetic acids useful in the treatment of diabetic complications | PFIZER INC. (US) | 1987-07-29 | — | — | EP | disclosed |
| US-4588591-A | Analgesic 2-oxa-spirocyclic compounds | THE UPJOHN COMPANY (US) | 1986-05-13 | — | — | US | disclosed |
| EP-0162690-A2 | 2-oxa-spirocyclic-benzeneacetamides and benzamides | THE UPJOHN COMPANY (US) | 1985-11-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071655-A1 | PROCESS FOR ENANTIOMERIC SEPARATION OF RACEMIC DIHYDRO-1,3,5, TRIAZINES VIA PREFERENTIAL CRYSTALLIZATION | IRS1, GPR119, INSR | LMNA 3711/4885KDM4E 4255/4885CYP3A4 916/4885 |
| US-20220324876-A1 | 4-SUBSTITUTED PYRANO[3,4,b]PYRAZINE KAPPA AGONISTS FOR TREATING DRUG DEPENDENCY | OPRK1, OPRD1, OPRM1 | LMNA 4824/4885KDM4E 1650/4885CYP3A4 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.