⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16287681 | 0.88 | — | — | |
| SCHEMBL231722 | 0.83 | — | — | |
| SCHEMBL10685835 | 0.81 | OPRM1 (0.39) | — | |
| SCHEMBL2105534 | 0.81 | — | — | |
| SCHEMBL7717461 | 0.78 | — | — | |
| SCHEMBL29283628 | 0.78 | — | — | |
| SCHEMBL30202941 | 0.78 | — | — | |
| SCHEMBL1016315 | 0.78 | — | — | |
| SCHEMBL4448679 | 0.78 | DNM1 (0.36) | — | |
| SCHEMBL28162402 | 0.78 | TRPM8 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2722051-B1 | Monomethylvaline compounds having phenylalanine side-chain modifications at the C-terminus | SEATTLE GENETICS INC (US) | 2018-11-07 | — | — | EP | disclosed |
| EP-2845866-B1 | Antibodies and immunoconjugates and uses therefor | GENENTECH INC (US) | 2017-05-03 | — | — | EP | disclosed |
| EP-1917020-B1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | SEATTLE GENETICS INC (US) | 2016-05-25 | — | — | EP | disclosed |
| EP-2447282-B1 | Anti-CD22 Antibodies, their Immunoconjugates and uses thereof | GENENTECH INC (US) | 2016-01-27 | — | — | EP | disclosed |
| EP-2353611-B1 | Drug conjugates and their use for treating cancer, an autoimmune disease or an infectious disease | SEATTLE GENETICS INC (US) | 2015-05-13 | — | — | EP | disclosed |
| EP-2446904-B1 | Anti-CD22 antibodies, their immunoconjugates and uses thereof | GENENTECH INC (US) | 2015-04-29 | — | — | EP | disclosed |
| EP-2845866-A1 | Antibodies and immunoconjugates and uses therefor | Genentech, Inc. (US) | 2015-03-11 | — | — | EP | disclosed |
| EP-2502938-B1 | Antibodies and immunoconjugates and uses therefor | GENENTECH INC (US) | 2015-02-18 | — | — | EP | disclosed |
| US-20150045409-A1 | AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-02-12 | — | — | US | disclosed |
| EP-2813493-A1 | AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL | Sumitomo Chemical Company Limited (JP) | 2014-12-17 | — | — | EP | disclosed |
| WO-2008052187-A2 | ANTIBODIES AND IMMUNOCONJUGATES AND USES THEREFOR | GENENTECH. INC. (US) | 2008-05-02 | — | — | WO | disclosed |
| WO-2007140371-A2 | ANTIBODIES AND IMMUNOCONJUGATES AND USES THEREFOR | GENENTECH, INC. (US) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007008848-A2 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE CARBOXY MODIFICATIONS AT THE C-TERMINUS | SEATTLE GENETICS, INC. (US) | 2007-01-18 | — | — | WO | disclosed |
| WO-2007008603-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | SEATTLE GENETICS, INC. (US) | 2007-01-18 | — | — | WO | disclosed |
| EP-1545613-A2 | DRUG CONJUGATES AND THEIR USE FOR TREATING CANCER, AN AUTOIMMUNE DISEASE OR AN INFECTIOUS DISEASE | Seattle Genetics, Inc. (US) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004010957-A2 | DRUG CONJUGATES AND THEIR USE FOR TREATING CANCER, AN AUTOIMMUNE DISEASE OR AN INFECTIOUS DISEASE | SEATTLE GENETICS, INC. (US) | 2004-02-05 | — | — | WO | disclosed |
| US-5378680-A | Dicarboximides and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1995-01-03 | — | — | US | disclosed |
| US-5176739-A | Plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1993-01-05 | — | — | US | disclosed |
| US-4867784-A | Cyclohexenone derivatives, preparation thereof and use thereof as herbicidal and plant growth regulator agents | BASF AKTIENGESELLSCHAFT (DE) | 1989-09-19 | — | — | US | disclosed |
| US-4804654-A | INSECTICIDES, MITICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-02-14 | — | — | US | disclosed |