Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176636 | 0.82 | MAPT (0.48) | AKR1C3AKR1C1MAPTALDH1A1RECQL | |
| SCHEMBL6523405 | 0.82 | TYR (0.47) | MAPTALDH1A1CYP2C9HCAR2CYP2D6 | |
| SCHEMBL5391413 | 0.76 | MCL1 (0.47) | AKR1C3AKR1C1MAPTALDH1A1RECQL | |
| SCHEMBL142531 | 0.74 | HDAC1 (0.56) | AKR1C3AKR1C1MAPTALDH1A1RECQL | |
| SCHEMBL7520233 | 0.74 | ALDH1A1 (0.50) | AKR1C3AKR1C1MAPTALDH1A1RECQL | |
| (Z)-1,2-Diphenylethene SCHEMBL28483617 | 0.72 | HDAC1 (0.61) | MAPTALDH1A1RECQLLMNACYP2C9 | |
| SCHEMBL792779 | 0.71 | AKR1C3 (0.56) | AKR1C3AKR1C1MAPTALDH1A1RECQL | |
| SCHEMBL1081471 | 0.71 | AKR1C3 (0.56) | AKR1C3AKR1C1MAPTALDH1A1RECQL | |
| SCHEMBL5982913 | 0.71 | AKR1C3 (0.56) | AKR1C3AKR1C1MAPTALDH1A1RECQL | |
| SCHEMBL1515664 | 0.71 | HTT (0.49) | MAPTALDH1A1RECQLLMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1829889-A2 | Kahalalide f and related compounds | PHARMA MAR, S.A. (ES) | 2007-09-05 | — | — | EP | claimed |
| US-11603487-B2 | Low molecular mass organic gelator wellbore stabilizers | HALLIBURTON ENERGY SERVICES, INC. (US) | 2023-03-14 | — | — | US | disclosed |
| US-11352538-B2 | Low molecular mass organic gelator viscosihiers | HALLIBURTON ENERGY SERVICES, INC. (US) | 2022-06-07 | — | — | US | disclosed |
| US-20210371720-A1 | LOW MOLECULAR MASS ORGANIC GELATOR WELLBORE STABILIZERS | HALLIBURTON ENERGY SERVICES, INC. | 2021-12-02 | — | — | US | disclosed |
| US-20210371721-A1 | LOW MOLECULAR MASS ORGANIC GELATOR VISCOSIFIERS | HALLIBURTON ENERGY SERVICES, INC. | 2021-12-02 | — | — | US | disclosed |
| EP-2258715-A1 | Kahalalide compounds | PHARMA MAR, S.A. (ES) | 2010-12-08 | — | — | EP | disclosed |
| US-7482429-B2 | Kahalalide F and related compounds | PHARMA MAR, S.A. (ES) | 2009-01-27 | — | — | US | disclosed |
| US-20080318849-A1 | Kahalalide F and Related Compounds | PHARMA MAR, S.A. (ES) | 2008-12-25 | — | — | US | disclosed |
| EP-1829889-A2 | Kahalalide f and related compounds | PHARMA MAR, S.A. (ES) | 2007-09-05 | — | — | EP | disclosed |
| EP-1254162-B1 | KAHALALIDE F AND RELATED COMPOUNDS | PHARMA MAR SA (ES) | 2007-08-29 | — | — | EP | disclosed |
| US-20040214755-A1 | Kahalalide f and related compounds | PHARMA MAR, S.A. (ES) | 2004-10-28 | — | — | US | disclosed |
| EP-0736036-B1 | KININOGEN INHIBITORS | FERRING BV (NL) | 2004-10-13 | — | — | EP | disclosed |
| EP-1254162-A2 | KAHALALIDE F AND RELATED COMPOUNDS | PHARMA MAR, S.A. (ES) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001058934-A2 | KAHALALIDE F AND RELATED COMPOUNDS | PHARMA MAR, S.A. (ES) | 2001-08-16 | — | — | WO | disclosed |
| WO-1995007291-A1 | KININOGEN INHIBITORS | FERRING B.V. (NL) | 1995-03-16 | — | — | WO | disclosed |
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | disclosed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | disclosed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214755-A1 | Kahalalide f and related compounds | KHK, HK1, HEXD | AKR1C3 759/4885AKR1C1 857/4885MAPT 3511/4885 |
| US-20080318849-A1 | Kahalalide F and Related Compounds | KHK, HK1, HEXD | AKR1C3 759/4885AKR1C1 857/4885MAPT 3511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.