Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 5/20 | 0.62 |
| ▸ | CISD1 | Q9NZ45 | 7/20 | 0.53 |
| ▸ | KDM6B | O15054 | 2/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11307705 | 0.88 | PLK1 (0.58) | PLK1CISD1ABL1HCAR3PPARA | |
| SCHEMBL11320812 | 0.88 | PLK1 (0.58) | PLK1CISD1ABL1HCAR3PPARA | |
| SCHEMBL11320571 | 0.88 | PLK1 (0.58) | PLK1CISD1ABL1HCAR3PPARA | |
| SCHEMBL11318599 | 0.88 | PLK1 (0.58) | PLK1CISD1ABL1HCAR3PPARA | |
| SCHEMBL11316566 | 0.88 | PLK1 (0.58) | PLK1CISD1ABL1HCAR3PPARA | |
| SCHEMBL11313036 | 0.88 | PLK1 (0.58) | PLK1CISD1ABL1HCAR3PPARA | |
| SCHEMBL11307858 | 0.88 | PLK1 (0.58) | PLK1CISD1ABL1HCAR3PPARA | |
| SCHEMBL11309283 | 0.88 | PLK1 (0.58) | PLK1CISD1ABL1HCAR3PPARA | |
| SCHEMBL11307721 | 0.88 | PLK1 (0.58) | PLK1CISD1ABL1HCAR3PPARA | |
| SCHEMBL11306890 | 0.88 | PLK1 (0.58) | PLK1CISD1ABL1HCAR3PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100322881-A1 | UVB FILTER BASED ON ASCORBIC ACID DERIVATIVES | MERCK PATENT GESELLSCHAFT (DE) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100322881-A1 | UVB FILTER BASED ON ASCORBIC ACID DERIVATIVES | C1R, VDR, CYP2R1 | PLK1 3510/4885CISD1 581/4885KDM6B 2796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.