Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 3/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086765 | 0.83 | TOP2A (0.46) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL631589 | 0.79 | TOP2A (0.48) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL630915 | 0.79 | TOP2A (0.48) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL378251 | 0.78 | TOP2A (0.50) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL16597500 | 0.78 | TOP2A (0.50) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL631865 | 0.76 | TOP2A (0.45) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL4971941 | 0.75 | TOP2A (0.44) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL10765254 | 0.74 | TOP2A (0.46) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL27618934 | 0.74 | TOP2A (0.46) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL29125125 | 0.74 | TOP2A (0.46) | TOP2ATOP2BALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071728-A1 | HYDANTOINS WITH INSULINOTROPIC ACTION | PHARMAMENS (FR) | 2007-06-28 | — | — | WO | disclosed |