Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3775347 | 0.86 | ALDH1A1 (0.46) | ALDH1A1CA12CA9LMNAMEN1 | |
| SCHEMBL4142104 | 0.81 | CA12 (0.40) | ALDH1A1CA12CA9ACHELMNA | |
| SCHEMBL16418145 | 0.78 | CASP3 (0.42) | ALDH1A1CA12CA9CYP1A2CYP2C9 | |
| SCHEMBL3777727 | 0.77 | ACHE (0.44) | ALDH1A1CA12CA9CYP1A2CYP2C9 | |
| SCHEMBL17983228 | 0.75 | ALDH1A1 (0.52) | ALDH1A1CA12CA9CYP1A2CYP2C9 | |
| SCHEMBL4773233 | 0.74 | KMT2A (0.38) | ALDH1A1CA12CA9ACHELMNA | |
| SCHEMBL18091410 | 0.74 | ALDH1A1 (0.46) | ALDH1A1CA9CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20033568 | 0.74 | ALDH1A1 (0.46) | ALDH1A1CA9CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6274051 | 0.74 | CYP1A2 (0.40) | ALDH1A1CA12CA9CYP1A2CYP2C9 | |
| SCHEMBL18121289 | 0.74 | ALDH1A1 (0.46) | ALDH1A1CA9CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230333095-A1 | METHOD FOR DETECTING AN ANALYTE OF INTEREST IN A SAMPLE | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2023-10-19 | — | — | US | disclosed |
| US-20230333095-A1 | METHOD FOR DETECTING AN ANALYTE OF INTEREST IN A SAMPLE | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2023-10-19 | — | — | US | disclosed |
| US-20100324305-A1 | PRODUCTION METHOD OF POLYCYCLIC LACTAMS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-12-23 | — | — | US | disclosed |
| US-20090118519-A1 | Production Method of Polycyclic Lactams | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-05-07 | — | — | US | disclosed |
| EP-2014647-A1 | PROCESS FOR PRODUCING POLYCYCLIC LACTAM | Sumitomo Chemical Company, Limited (JP) | 2009-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118519-A1 | Production Method of Polycyclic Lactams | MRPL21, COASY, ASNS | ALDH1A1 1979/4885CA12 786/4885CA9 216/4885 |
| US-20100324305-A1 | PRODUCTION METHOD OF POLYCYCLIC LACTAMS | COASY, MRPL21, ASNS | ALDH1A1 1821/4885CA12 784/4885CA9 221/4885 |
| US-20230333095-A1 | METHOD FOR DETECTING AN ANALYTE OF INTEREST IN A SAMPLE | ENTPD5, KLK3, GUSB | ALDH1A1 292/4885CA12 7/4885CA9 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.