SCHEMBL37832

SCHEMBL37832

Cc1cc(C(C)(C)C)nc(C(C)(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
CA2 P00918 1/20 0.40
POLB P06746 1/20 0.40
TYR P14679 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HSD17B10 Q99714 1/20 0.40
KDM4E B2RXH2 1/20 0.39
TSHR P16473 1/20 0.39
CYP1A2 P05177 2/20 0.36
CYP2A6 P11509 2/20 0.36
HMGCR P04035 3/20 0.35
CCR4 P51679 1/20 0.35
NOS3 P29474 2/20 0.35
NOS2 P35228 2/20 0.35
NOS1 P29475 1/20 0.35
HRH4 Q9H3N8 1/20 0.33
HSPA5 P11021 1/20 0.32
NQO2 P16083 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL10759230 0.97 HSD17B10 (0.39) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL28111108 0.90 HSD17B10 (0.35) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL15726902 0.88 HSP90AA1 (0.45) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL2897692 0.88 CCR4 (0.41) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL16852469 0.88 SMN1; SMN2 (0.38) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL16350907 0.88 HSD17B10 (0.34) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL12871593 0.87 NOS3 (0.46) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL23872483 0.83 HRH4 (0.36) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL18701490 0.83 ALDH1A1 (0.43) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL19156103 0.83 KDM4E (0.38) ALDH1A1CA2POLBTYRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4730 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577236-B2 Processes for preparation of Tezacaftor LAURUS LABS LIMITED (IN) 2026-03-17 US claimed
US-12559514-B2 Synthesis of fluorinated nucleotides MERCK SHARP & DOHME LLC (US) 2026-02-24 US claimed
CN-120059488-A Near infrared two-region albumin efficient in-situ targeted cyanine dye and preparation method and application thereof 长春吉智荧科生物科技有限公司 2025-05-30 CN claimed
CN-119954706-A Nine-methyl alkyne dye probe and application thereof in disease diagnosis 吉林大学 2025-05-09 CN claimed
CN-119874493-A Novel method for synthesizing alpha, beta-unsaturated ketone 广西大学 2025-04-25 CN claimed
US-20250115601-A1 PROCESS FOR THE PREPARATION OF FINERENONE AND INTERMEDIATES THEREOF ALIVUS LIFE SCIENCES LIMITED (IN) 2025-04-10 US claimed
EP-4526302-A1 PROCESS FOR THE PREPARATION OF FINERENONE AND INTERMEDIATES THEREOF Alivus Life Sciences Limited (IN) 2025-03-26 EP claimed
CN-114591223-B Beta-lactamase inhibitor compounds 恩塔西斯治疗有限公司 2025-01-24 CN claimed
CN-119192221-A Method for synthesizing bryoid A ring fragment key intermediate and A ring C1-C14 fragment 四川大学 2024-12-27 CN claimed
US-20240400784-A1 Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition LG CHEM, LTD. (KR) 2024-12-05 US claimed
US-5214134-A PROCESS OF LINKING NUCLEOSIDES WITH A SILOXANE BRIDGE STERLING WINTHROP INC. (US) 1993-05-25 US claimed
WO-1993002110-A1 LIVING CARBOCATIONIC POLYMERIZATION PROCESS EXXON CHEMICAL PATENTS INC. (US) 1993-02-04 WO claimed
EP-0242289-B1 PROCESS FOR THE PREPARATION OF OXAZINOBENZOTHIAZINE 6,6-DIOXIDE DERIVATIVES LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 1992-08-19 EP claimed
WO-1992004364-A1 A METHOD OF LINKING NUCLEOSIDES WITH A SILOXANE BRIDGE STERLING WINTHROP INC. (US) 1992-03-19 WO claimed
EP-0264183-B1 DERIVATIVES OF 5-METHYL-10,11-DIHYDRO-5H-DIBENZO-(A,D) CYCLOHEPTEN-5,10-IMINE MERCK & CO. INC. (US) 1992-01-15 EP claimed
WO-1991011468-A1 NEW THERMOPLASTIC ELASTOMERS THE UNIVERSITY OF AKRON (US) 1991-08-08 WO claimed
US-4946899-A CARBOCATIONIC POLYMERIZATION INVOLVING HOMOPOLYMERIZATION OF ELASTOMER FOLLOWED BY COPOLYMERIZATION TO ADD GLASSY SEGMENTS; FORMING LIVING POLYMERS WITH A METAL HALIDE, PROMOTER AND SOLVENT MIXTURE THE UNIVERSITY OF AKRON (US) 1990-08-07 US claimed
US-4830846-A SALT FORMATION AND NEUTRALIZATION THE DOW CHEMICAL COMPANY (US) 1989-05-16 US claimed
US-4797482-A Process for the preparation of oxazinobenzothiazine 6,6-dioxide derivatives PROVESAN S.A. (CH) 1989-01-10 US claimed
EP-0242289-A1 Process for the preparation of oxazinobenzothiazine 6,6-dioxide derivatives LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 1987-10-21 EP claimed