SCHEMBL2897692

SCHEMBL2897692

CC(C)(C)c1cccc(C(C)(C)C)n1.Cc1cc(C(C)(C)C)nc(C(C)(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR4 P51679 2/20 0.41
KDM4E B2RXH2 1/20 0.38
TSHR P16473 2/20 0.37
ACHE P22303 1/20 0.36
NQO2 P16083 1/20 0.35
PSMB5 P28074 2/20 0.35
SYK P43405 1/20 0.35
CYP2A6 P11509 4/20 0.35
CYP1A2 P05177 4/20 0.35
TDP1 Q9NUW8 1/20 0.34
HSD17B10 Q99714 2/20 0.34
ALDH1A1 P00352 3/20 0.33
LMNA P02545 2/20 0.33
GAA P10253 2/20 0.33
CA2 P00918 1/20 0.33
POLB P06746 1/20 0.33
TYR P14679 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TP53 P04637 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37832 0.88 ALDH1A1 (0.40) CCR4KDM4ETSHRNQO2CYP2A6
SCHEMBL9109264 0.87 NOS3 (0.40) CCR4KDM4ETSHRACHENQO2
Bromide SCHEMBL10759230 0.85 HSD17B10 (0.39) CCR4KDM4ETSHRNQO2CYP2A6
SCHEMBL42955 0.85 PGK1 (0.39) CCR4KDM4ETSHRSYKHSD17B10
Iodide SCHEMBL2346492 0.83 PGK1 (0.38) CCR4KDM4ETSHRSYKHSD17B10
Hydrochloric Acid SCHEMBL30595152 0.83 PGK1 (0.38) CCR4KDM4ETSHRSYKALDH1A1
SCHEMBL28111108 0.79 HSD17B10 (0.35) CCR4KDM4ETSHRCYP2A6CYP1A2
SCHEMBL15726902 0.77 HSP90AA1 (0.45) KDM4ETSHRCYP1A2HSD17B10ALDH1A1
SCHEMBL16350907 0.77 HSD17B10 (0.34) CCR4KDM4ETSHRHSD17B10ALDH1A1
SCHEMBL18701490 0.77 ALDH1A1 (0.43) CCR4KDM4ETSHRACHENQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0594693-B1 LIVING CARBOCATIONIC POLYMERIZATION PROCESS EXXON CHEMICAL PATENTS INC (US) 1997-12-10 EP claimed
US-7781483-B2 Benzopyran compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-08-24 US disclosed